Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes.
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The inotropic effect of cardioactive glycosides in ventricular myocytes requires Na+-Ca2+ exchanger functionDepolarization-induced calcium responses in sympathetic neurons: relative contributions from Ca2+ entry, extrusion, ER/mitochondrial Ca2+ uptake and release, and Ca2+ bufferingGenetic evidence in the mouse solidifies the calcium hypothesis of myofiber death in muscular dystrophyModeling effects of L-type ca(2+) current and na(+)-ca(2+) exchanger on ca(2+) trigger flux in rabbit myocytes with realistic T-tubule geometriesA mathematical model of the murine ventricular myocyte: a data-driven biophysically based approach applied to mice overexpressing the canine NCX isoform.A transmural gradient in the cardiac Na/K pump generates a transmural gradient in Na/Ca exchange.A computational model of the ionic currents, Ca2+ dynamics and action potentials underlying contraction of isolated uterine smooth muscle.Computational model of the cAMP-mediated sensory response and calcium-dependent adaptation in vertebrate olfactory receptor neurons.A mathematical treatment of integrated Ca dynamics within the ventricular myocyte.Activation of the cardiac Na(+)-Ca(2+) exchanger by sorcin via the interaction of the respective Ca(2+)-binding domains.Data-based theoretical identification of subcellular calcium compartments and estimation of calcium dynamics in cardiac myocytes.NCLX: the mitochondrial sodium calcium exchanger.Regulation of cardiac sarcoplasmic reticulum Ca release by luminal [Ca] and altered gating assessed with a mathematical model.Contribution of the Na+/Ca2+ exchanger to rapid Ca2+ release in cardiomyocytes.Cardiac Na+-Ca2+ exchanger current induced by tyrphostin tyrosine kinase inhibitors.Calcium and arrhythmogenesis.The role of cellular coupling in the spontaneous generation of electrical activity in uterine tissue.Proton-sensing Ca2+ binding domains regulate the cardiac Na+/Ca2+ exchanger.Residues 248-252 and 300-304 of the cardiac Na+/Ca2+ exchanger are involved in its regulation by phospholemman.Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model.New insights into the molecular and cellular workings of the cardiac Na+/Ca2+ exchanger.Modelling calcium microdomains using homogenisationToward an integrative computational model of the Guinea pig cardiac myocyte.Vascular Na+/Ca2+ exchanger: implications for the pathogenesis and therapy of salt-dependent hypertension.Allosteric activation of sodium-calcium exchange activity by calcium: persistence at low calcium concentrations.Calcium clearance mechanisms of mouse sperm.Calcium transport mechanisms of PC12 cells.There and back again: Iterating between population-based modeling and experiments reveals surprising regulation of calcium transients in rat cardiac myocytes.Na:Ca stoichiometry and cytosolic Ca-dependent activation of NCX in intact cardiomyocytes.Regulation of Na+/Ca2+ exchange current in the normal and failing heart.Conformational changes of a Ca2+-binding domain of the Na+/Ca2+ exchanger monitored by FRET in transgenic zebrafish heart.Excitation-contraction coupling and mitochondrial energetics.Mitochondrial calcium uptake.Na+ transport in cardiac myocytes; Implications for excitation-contraction coupling.Force frequency relationship of the human ventricle increases during early postnatal developmentInterpreting genetic effects through models of cardiac electromechanics.Na+ dysregulation coupled with Ca2+ entry through NCX1 promotes muscular dystrophy in mice.Modeling CICR in rat ventricular myocytes: voltage clamp studies.Sodium-calcium exchange inhibitors: therapeutic potential in cardiovascular diseases.Cardiac sodium-calcium exchanger is regulated by allosteric calcium and exchanger inhibitory peptide at distinct sites.
P2860
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P2860
Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Allosteric regulation of Na/Ca ...... Ca in intact cardiac myocytes.
@ast
Allosteric regulation of Na/Ca ...... Ca in intact cardiac myocytes.
@en
type
label
Allosteric regulation of Na/Ca ...... Ca in intact cardiac myocytes.
@ast
Allosteric regulation of Na/Ca ...... Ca in intact cardiac myocytes.
@en
prefLabel
Allosteric regulation of Na/Ca ...... Ca in intact cardiac myocytes.
@ast
Allosteric regulation of Na/Ca ...... Ca in intact cardiac myocytes.
@en
P2093
P2860
P356
P1476
Allosteric regulation of Na/Ca ...... Ca in intact cardiac myocytes
@en
P2093
K D Philipson
K S Ginsburg
T R Shannon
P2860
P304
P356
10.1085/JGP.117.2.119
P577
2001-02-01T00:00:00Z