Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation.
about
Network analysis of skin tumor progression identifies a rewired genetic architecture affecting inflammation and tumor susceptibilityGranzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysisGranzymes: a family of lymphocyte granule serine proteasesRecombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of themEvaluating the cytotoxicity of innate immune effector cells using the GrB ELISPOT assayThe Granzyme B ELISPOT assay: an alternative to the 51Cr-release assay for monitoring cell-mediated cytotoxicityProtease signalling: the cutting edgeVisualization of cytolytic T cell differentiation and granule exocytosis with T cells from mice expressing active fluorescent granzyme BStructure of granzyme C reveals an unusual mechanism of protease autoinhibitionProcessing and activation of pro-interleukin-16 by caspase-3Influence of splenectomy in patients with liver cirrhosis and hypersplenism.Cell adhesion and the immune system: a case study using earthworms.NK cells and apoptosis.Anti-viral strategies of cytotoxic T lymphocytes are manifested through a variety of granule-bound pathways of apoptosis induction.Granzyme G is expressed in the two-cell stage mouse embryo and is required for the maternal-zygotic transition.The relative role of lymphocyte granule exocytosis versus death receptor-mediated cytotoxicity in viral pathophysiologyGranzyme A activates another way to dieNatural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells.Perforin: more than just a pore-forming protein.Longitudinal, noninvasive imaging of T-cell effector function and proliferation in living subjects.Loss of the perforin cytotoxic pathway predisposes mice to experimental cytomegalovirus retinitis.Granzyme B mediates both direct and indirect cleavage of extracellular matrix in skin after chronic low-dose ultraviolet light irradiation.Cellular proteolysis. An overview.The facts of death.Internal water molecules and H-bonding in biological macromolecules: a review of structural features with functional implications.Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo.Processing of Neutrophil α-Defensins Does Not Rely on Serine Proteases In Vivo.Interleukin-21 administration to rhesus macaques chronically infected with simian immunodeficiency virus increases cytotoxic effector molecules in T cells and NK cells and enhances B cell function without increasing immune activation or viral replicGranzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes.Immunohistochemical localization of granzyme B antigen in cytotoxic cells in human tissues.Expression of cytolytic mediators by synovial fluid lymphocytes in rheumatoid arthritis.A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity.The lytic granules of natural killer cells are dual-function organelles combining secretory and pre-lysosomal compartments.Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria.Assessment of cytotoxic T-lymphocyte phenotype using the specific markers granzyme B and TIA-1 in cervical neoplastic lesions.Natural killer (NK)-like cytotoxicity of murine intraepithelial lymphocytes in the small intestine (iIEL) and the effect of the serine proteases.Cysteine cathepsins: regulators of antitumour immune response.The neutrophil: mechanisms of controlling periodontal bacteria.Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injuryPrevention of infectious diseases in older adults through immunization: the challenge of the senescent immune response.
P2860
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P2860
Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh
1988年學術文章
@zh-hant
name
Granzymes, a family of serine ...... n T cell receptor stimulation.
@ast
Granzymes, a family of serine ...... n T cell receptor stimulation.
@en
type
label
Granzymes, a family of serine ...... n T cell receptor stimulation.
@ast
Granzymes, a family of serine ...... n T cell receptor stimulation.
@en
prefLabel
Granzymes, a family of serine ...... n T cell receptor stimulation.
@ast
Granzymes, a family of serine ...... n T cell receptor stimulation.
@en
P2860
P1476
Granzymes, a family of serine ...... n T cell receptor stimulation.
@en
P2093
P2860
P356
10.1111/J.1600-065X.1988.TB00749.X
P50
P577
1988-03-01T00:00:00Z