Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity. - Wikidata - wikimedia - TriplyDB

Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity.

Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity.

http://www.wikidata.org/entity/Q36447158

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Molecular mechanisms of large-conductance ca (2+) -activated potassium channel activation by ginseng gintonin Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution Structure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channel Gating mechanism of BK (Slo1) channels: so near, yet so far The RCK2 domain of the human BKCa channel is a calcium sensor Beta1 subunits facilitate gating of BK channels by acting through the Ca2+, but not the Mg2+, activating mechanisms Structural determinants for functional coupling between the beta and alpha subunits in the Ca2+-activated K+ (BK) channel BK channels: multiple sensors, one activation gate Stimulatory action of internal protons on Slo1 BK channels Structural correlates of selectivity and inactivation in potassium channels.Modeling spike-train processing in the cerebellum granular layer and changes in plasticity reveal single neuron effects in neural ensembles Generation of functional fluorescent BK channels by random insertion of GFP variants RACK1 is a BKCa channel binding protein.Zn2+ activates large conductance Ca2+-activated K+ channel via an intracellular domain.A BK (Slo1) channel journey from molecule to physiology.Coupling and cooperativity in voltage activation of a limited-state BK channel gating in saturating Ca2+.Structural determinants of phosphatidylinositol 4,5-bisphosphate (PIP2) regulation of BK channel activity through the RCK1 Ca2+ coordination site.Cryo-EM structure of the open high-conductance Ca2+-activated K+ channel The RCK1 domain of the human BKCa channel transduces Ca2+ binding into structural rearrangements BK channel activation: structural and functional insights TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology.Ion sensing in the RCK1 domain of BK channels.Setting the stage for molecular dissection of the regulatory components of BK channels.Single-channel kinetics of BK (Slo1) channels.Metal-driven operation of the human large-conductance voltage- and Ca2+-dependent potassium channel (BK) gating ring apparatus.Mg(2+) binding to open and closed states can activate BK channels provided that the voltage sensors are elevated Allosteric modulation of ion channels: the case of maxi-K.The contribution of RCK domains to human BK channel allosteric activation The BKCa channel's Ca2+-binding sites, multiple sites, multiple ions Barium ions selectively activate BK channels via the Ca2+-bowl site Effects of multiple metal binding sites on calcium and magnesium-dependent activation of BK channels Intra- and intersubunit cooperativity in activation of BK channels by Ca2+A tail of multiple calcium-sensing domains Mechanisms of two modulatory actions of the channel-binding protein Slob on the Drosophila Slowpoke calcium-dependent potassium channel A role for the S0 transmembrane segment in voltage-dependent gating of BK channels.Modulation of the conductance-voltage relationship of the BK Ca channel by mutations at the putative flexible interface between two RCK domains.Cysteine modification alters voltage- and Ca(2+)-dependent gating of large conductance (BK) potassium channels.Slo1 tail domains, but not the Ca2+ bowl, are required for the beta 1 subunit to increase the apparent Ca2+ sensitivity of BK channels Divalent cation sensitivity of BK channel activation supports the existence of three distinct binding sites.Mapping the BKCa channel's "Ca2+ bowl": side-chains essential for Ca2+ sensing.

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P2860

Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity.

http://www.wikidata.org/entity/Q36447158

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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2002年學術文章

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2002年學術文章

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name

Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity.

@ast

Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity.

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type

label

Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity.

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Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity.

@en

prefLabel

Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity.

@ast

Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity.

@en

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The Journal of General Physiology

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Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity.

@en

P2093

Anne M Rapin

http://www.w3.org/2001/XMLSchema#string

Daniel H Cox

http://www.w3.org/2001/XMLSchema#string

Ericka C Holmstrand

http://www.w3.org/2001/XMLSchema#string

Lin Bao

http://www.w3.org/2001/XMLSchema#string

P2860

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

A calcium switch for the functional coupling between alpha (hslo) and beta subunits (KV,Ca beta) of maxi K channels

A novel calcium-sensing domain in the BK channel.

Structure of the RCK domain from the E. coli K+ channel and demonstration of its presence in the human BK channel

Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin

A helical region in the C terminus of small-conductance Ca2+-activated K+ channels controls assembly with apo-calmodulin

Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

Role of the S4 segment in a voltage-dependent calcium-sensitive potassium (hSlo) channel

mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels

Slo3, a novel pH-sensitive K+ channel from mammalian spermatocytes

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173-189

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