A cluster of oppositely imprinted transcripts at the Gnas locus in the distal imprinting region of mouse chromosome 2
about
A novel STX16 deletion in autosomal dominant pseudohypoparathyroidism type Ib redefines the boundaries of a cis-acting imprinting control element of GNASIsoform-specific imprinting of the human PEG1/MEST geneDiverse splicing mechanisms fuse the evolutionarily conserved bicistronic MOCS1A and MOCS1B open reading framesImprinting of the human L3MBTL gene, a polycomb family member located in a region of chromosome 20 deleted in human myeloid malignanciesAn imprinted transcript, antisense to Nesp, adds complexity to the cluster of imprinted genes at the mouse Gnas locusNondisjunction and transmission ratio distortion ofChromosome 2 in a (2.8) Robertsonian translocation mouse strain.The GNAS complex locus and human diseases associated with loss-of-function mutations or epimutations within this imprinted geneGene Dosage Effects at the Imprinted Gnas ClusterProgramming and inheritance of parental DNA methylomes in vertebratesTwo overlapping reading frames in a single exon encode interacting proteins--a novel way of gene usageGNAS locus and pseudohypoparathyroidismXLalphas, the extra-long form of the alpha-subunit of the Gs G protein, is significantly longer than suspected, and so is its companion AlexPaternal uniparental isodisomy of chromosome 20q--and the resulting changes in GNAS1 methylation--as a plausible cause of pseudohypoparathyroidism.Identification of the control region for tissue-specific imprinting of the stimulatory G protein alpha-subunitTransgenic overexpression of the extra-large Gsα variant XLαs enhances Gsα-mediated responses in the mouse renal proximal tubule in vivoA tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chipMaternal inheritance of the Gnas cluster mutation Ex1A-T affects size, implicating NESP55 in growthPaternal versus maternal transmission of a stimulatory G-protein alpha subunit knockout produces opposite effects on energy metabolismTargeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-IbPost-natal imprinting: evidence from marsupialsAntisense transcripts with FANTOM2 clone set and their implications for gene regulation.Transcriptome-wide identification of novel imprinted genes in neonatal mouse brainAt least ten genes define the imprinted Dlk1-Dio3 cluster on mouse chromosome 12qF1Imprinted genes: identification by chromosome rearrangements and post-genomic strategies.A comprehensive transcript map of the mouse Gnas imprinted complex.Identification of a large novel imprinted gene cluster on mouse proximal chromosome 6.Imprinted Nesp55 influences behavioral reactivity to novel environmentsAlternative Gnas gene products have opposite effects on glucose and lipid metabolism.The impact of genomic imprinting for neurobehavioral and developmental disorders.A novel variant of Inpp5f is imprinted in brain, and its expression is correlated with differential methylation of an internal CpG island.Variable imprinting of the heterotrimeric G protein G(s) alpha-subunit within different segments of the nephron.Programming and inheritance of parental DNA methylomes in mammalsAnalysis of GNAS1 and overlapping transcripts identifies the parental origin of mutations in patients with sporadic Albright hereditary osteodystrophy and reveals a model system in which to observe the effects of splicing mutations on translated andIdentification of a methylation imprint mark within the mouse Gnas locus.The impact of assisted reproductive technologies on genomic imprinting and imprinting disorders.Deletion of the noncoding GNAS antisense transcript causes pseudohypoparathyroidism type Ib and biparental defects of GNAS methylation in cisThe evolution of controlled multitasked gene networks: the role of introns and other noncoding RNAs in the development of complex organisms.The role of GNAS and other imprinted genes in the development of obesity.Postnatal changes in the expression pattern of the imprinted signalling protein XLαs underlie the changing phenotype of deficient mice.Evidence for a prostate cancer-susceptibility locus on chromosome 20.
P2860
Q24531505-5BF76918-52A6-48F1-BB9E-610311B6E361Q24534306-19D68AE4-DE93-4AE3-B9FB-F3728CEA7EFAQ24539783-070D7BA4-BD6C-4D0D-B3DF-5B44ACF12A09Q24562340-75148CEA-C268-4EB8-87E6-0EB60A71403FQ24678820-27A5D1D2-F6EB-4FB2-8823-63FAE4C1F771Q25255774-B4FD9E6E-E217-4399-8FA6-A918FE35123FQ26852157-6B58B55A-24E6-4ECA-BB94-7084A57D8E83Q27316512-AC491D32-02C7-49E4-90DC-17C5C8769E77Q28081962-27DAE7D0-BD45-458C-BBBE-8989473BE59BQ28205745-53E752A7-59EF-4578-A22E-36ABAF705D1AQ28235038-D3C600BC-C204-4518-8092-115F19F57507Q28262259-AEFD4F9D-B898-4500-8BF6-E5FFF3905DF8Q28362180-788EC5A8-EF90-4471-9DEE-AEA56F31449DQ28508007-C7F1AB74-8207-4B4C-87D3-3C0C465FD051Q28564775-56549789-37E1-486E-A463-5F90EE507FA8Q28592430-4B70CB68-0B37-41C7-9848-13C0119DAFBFQ28592629-B5577BA8-C60E-4E66-8DC8-9A1AD2FBFD42Q28593512-1BF02F84-98FE-4282-9566-DAD974F52E01Q28593878-7BD63A28-841A-43F7-B782-4EE43B5AB376Q28655490-A18B2D97-A7E1-45CD-BCA5-818F6199A46BQ31147226-6F781CD4-AF1A-4BEF-B702-3BF14B9EB7C2Q33389173-3BCB2341-947F-4A7A-AB98-F5057036FDB1Q33405733-07791E54-9647-430C-95F9-1AD3FA2BA3A0Q33622341-A05E99A1-7551-4BAC-94EA-AA5F2D9BC408Q33678495-88226E57-0B80-4B02-A944-4D4B3D7CEF5DQ33680910-F71BC165-4B88-4D94-8F82-D9579F531471Q33724476-B8707F42-C8FE-48F3-B4BD-D60DAEE7C073Q33821507-0316A073-0C58-4ADF-B4CF-90E79A51B011Q33843172-53449D24-2750-4A02-8C3E-0A593F257258Q33862945-502954F9-0144-4EB8-A490-EE09FD179850Q33883551-CCD07AE5-71B7-4E1E-B64E-A29D6A8BC0D8Q33894408-745A572F-A4D0-4BB2-872D-E05AC4E6B4D8Q33905114-36F975CB-CE65-4D72-8EC9-F0A64D4F3DC8Q33964982-CB09A5AA-78D4-40F2-B2F4-ADAA96E52A02Q34011361-38D31319-CCF5-41BF-81E9-DB21F1C92FB6Q34032076-952CD577-028F-454C-98F6-DD1822420378Q34086807-72E5CDE3-D221-4758-9901-6970D806B107Q34099397-BF12A09E-5391-4683-B389-EA69D86E4673Q34130616-CC502B0B-1E54-4B34-A520-53DA7028EF43Q34141928-51AC60C9-D11C-4275-8A6C-DAC28337F9EA
P2860
A cluster of oppositely imprinted transcripts at the Gnas locus in the distal imprinting region of mouse chromosome 2
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
A cluster of oppositely imprin ...... g region of mouse chromosome 2
@ast
A cluster of oppositely imprin ...... g region of mouse chromosome 2
@en
type
label
A cluster of oppositely imprin ...... g region of mouse chromosome 2
@ast
A cluster of oppositely imprin ...... g region of mouse chromosome 2
@en
prefLabel
A cluster of oppositely imprin ...... g region of mouse chromosome 2
@ast
A cluster of oppositely imprin ...... g region of mouse chromosome 2
@en
P2093
P2860
P356
P1476
A cluster of oppositely imprin ...... g region of mouse chromosome 2
@en
P2093
Beechey CV
Williamson CM
P2860
P304
P356
10.1073/PNAS.96.7.3830
P407
P577
1999-03-01T00:00:00Z