Vascular integrins in tumor angiogenesis: mediators and therapeutic targets.
about
Cooperation between integrin alphavbeta3 and VEGFR2 in angiogenesisLipoxins: nature's way to resolve inflammationMVL-PLA2, a snake venom phospholipase A2, inhibits angiogenesis through an increase in microtubule dynamics and disorganization of focal adhesionsNMR structure and dynamics of recombinant wild type and mutated jerdostatin, a selective inhibitor of integrin α1β1The integrin antagonist cilengitide activates alphaVbeta3, disrupts VE-cadherin localization at cell junctions and enhances permeability in endothelial cellsCombination of RGD compound and low-dose paclitaxel induces apoptosis in human glioblastoma cellsMechanisms of integrin-vascular endothelial growth factor receptor cross-activation in angiogenesis.Engineered cystine-knot peptides that bind alpha(v)beta(3) integrin with antibody-like affinities.Engineered cystine knot peptides that bind alphavbeta3, alphavbeta5, and alpha5beta1 integrins with low-nanomolar affinity.CC-PLA2-1 and CC-PLA2-2, two Cerastes cerastes venom-derived phospholipases A2, inhibit angiogenesis both in vitro and in vivo.Alphav beta3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis.Engineered knottin peptides: a new class of agents for imaging integrin expression in living subjects.Intravascularly administered RGD-displaying measles viruses bind to and infect neovessel endothelial cells in vivoThe four-transmembrane protein MAL2 and tumor protein D52 (TPD52) are highly expressed in colorectal cancer and correlated with poor prognosisFunctional mutation of multiple solvent-exposed loops in the Ecballium elaterium trypsin inhibitor-II cystine knot miniprotein.Integrin Targeted MR Imaging.Integrin alpha(v)beta(3)-Targeted Cancer Therapy.Mesenchymal migration as a therapeutic target in glioblastoma.Suppression of integrin alpha3beta1 in breast cancer cells reduces cyclooxygenase-2 gene expression and inhibits tumorigenesis, invasion, and cross-talk to endothelial cells.Vitronectin increases vascular permeability by promoting VE-cadherin internalization at cell junctions.A dual-labeled knottin peptide for PET and near-infrared fluorescence imaging of integrin expression in living subjects.T-CAM, a fastatin-FIII 9-10 fusion protein, potently enhances anti-angiogenic and anti-tumor activity via alphavbeta3 and alpha5beta1 integrins.Evaluation of α2-integrin expression as a biomarker for tumor growth inhibition for the investigational integrin inhibitor E7820 in preclinical and clinical studies.Conformational mAb as a tool for integrin ligand discoveryDisruption of the endothelial barrier by proteases from the bacterial pathogen Pseudomonas aeruginosa: implication of matrilysis and receptor cleavageRho/MRTF-A-Induced Integrin Expression Regulates Angiogenesis in Differentiated Multipotent Mesenchymal Stem CellsProstaglandins in cancer cell adhesion, migration, and invasionDiscovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of α3 integrin-expressing human tumors.N-cadherin as a therapeutic target in cancer.Minute dosages of alpha(nu)beta3-targeted fumagillin nanoparticles impair Vx-2 tumor angiogenesis and development in rabbitsVE-cadherin cleavage by ovarian cancer microparticles induces β-catenin phosphorylation in endothelial cellsIntegrin affinity modulation in angiogenesisalpha5beta1 Integrin blockade inhibits lymphangiogenesis in airway inflammation.High sensitivity: high-resolution SPECT-CT/MR molecular imaging of angiogenesis in the Vx2 modelThe role of integrins in cancer and the development of anti-integrin therapeutic agents for cancer therapy.Engineered cystine-knot miniproteins for diagnostic applications.Non-invasive Monitoring of Angiogenesis in Cardiology.Regulation of endothelial cell functions by basement membrane- and arachidonic acid-derived products.The regulatory function of SPARC in vascular biology.Cilengitide: a prototypic integrin inhibitor for the treatment of glioblastoma and other malignancies.
P2860
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P2860
Vascular integrins in tumor angiogenesis: mediators and therapeutic targets.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Vascular integrins in tumor angiogenesis: mediators and therapeutic targets.
@ast
Vascular integrins in tumor angiogenesis: mediators and therapeutic targets.
@en
type
label
Vascular integrins in tumor angiogenesis: mediators and therapeutic targets.
@ast
Vascular integrins in tumor angiogenesis: mediators and therapeutic targets.
@en
prefLabel
Vascular integrins in tumor angiogenesis: mediators and therapeutic targets.
@ast
Vascular integrins in tumor angiogenesis: mediators and therapeutic targets.
@en
P1476
Vascular integrins in tumor angiogenesis: mediators and therapeutic targets.
@en
P2093
Curzio Rüegg
Gian Carlo Alghisi
P304
P356
10.1080/10623320600698037
P577
2006-03-01T00:00:00Z