The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine.
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Tolerogenic dendritic cells and negative vaccination in transplantation: from rodents to clinical trialsAdjuvants: Classification, Modus Operandi, and LicensingPathogen-Associated Molecular Patterns Induced Crosstalk between Dendritic Cells, T Helper Cells, and Natural Killer Helper Cells Can Improve Dendritic Cell VaccinationTLR7/9 versus TLR3/MDA5 signaling during virus infections and diabetesTargeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective ImmunitySynthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaquesA tonsillar PolyICLC/AT-2 SIV therapeutic vaccine maintains low viremia following antiretroviral therapy cessationPolyICLC Exerts Pro- and Anti-HIV Effects on the DC-T Cell Milieu In Vitro and In VivoHarnessing the Microbiome to Enhance Cancer ImmunotherapyImmunogenicity of DNA vaccines encoding simian immunodeficiency virus antigen targeted to dendritic cells in rhesus macaquesImmune Adjuvant Effect of Molecularly-defined Toll-Like Receptor LigandsAn adjuvant for the induction of potent, protective humoral responses to an H5N1 influenza virus vaccine with antigen-sparing effect in mice.Activation of the innate immune system provides broad-spectrum protection against influenza A viruses with pandemic potential in mice.Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-targeted antigens by synergistic toll-like receptor ligands.Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells.CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells.Vaccine-induced myeloid cell population dampens protective immunity to SIVDendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8+ T cells.Effects of human respiratory syncytial virus, metapneumovirus, parainfluenza virus 3 and influenza virus on CD4+ T cell activation by dendritic cells.Induction of tumor-specific acquired immunity against already established tumors by selective stimulation of innate DEC-205(+) dendritic cells.Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population.Vaccine strategies utilizing C-type lectin receptors on dendritic cells in vivoMucosal imprinting of vaccine-induced CD8⁺ T cells is crucial to inhibit the growth of mucosal tumorsDendritic cell-based human immunodeficiency virus vaccine.Toll-like receptor agonists in cancer therapy.Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo.Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-alpha and IFN-gamma dependent mannersIL-10 production differentially influences the magnitude, quality, and protective capacity of Th1 responses depending on the vaccine platform.Targeting of antigens to skin dendritic cells: possibilities to enhance vaccine efficacyImmunomodulatory effects of dsRNA and its potential as vaccine adjuvant.Polyelectrolyte capsules-containing HIV-1 p24 and poly I:C modulate dendritic cells to stimulate HIV-1-specific immune responses.Macrophage- and neutrophil-derived TNF-α instructs skin langerhans cells to prime antiviral immune responsesToll-like receptor agonists: are they good adjuvants?Classical Flt3L-dependent dendritic cells control immunity to protein vaccineThe human cancer antigen mesothelin is more efficiently presented to the mouse immune system when targeted to the DEC-205/CD205 receptor on dendritic cells.The combination of early and rapid type I IFN, IL-1α, and IL-1β production are essential mediators of RNA-like adjuvant driven CD4+ Th1 responsesHMGB1-derived peptide acts as adjuvant inducing immune responses to peptide and protein antigen.Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti-human DEC205 monoclonal antibodyAntibody-antigen-adjuvant conjugates enable co-delivery of antigen and adjuvant to dendritic cells in cis but only have partial targeting specificity.Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance.
P2860
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P2860
The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
The microbial mimic poly IC in ...... ndritic cell targeted vaccine.
@ast
The microbial mimic poly IC in ...... ndritic cell targeted vaccine.
@en
type
label
The microbial mimic poly IC in ...... ndritic cell targeted vaccine.
@ast
The microbial mimic poly IC in ...... ndritic cell targeted vaccine.
@en
prefLabel
The microbial mimic poly IC in ...... ndritic cell targeted vaccine.
@ast
The microbial mimic poly IC in ...... ndritic cell targeted vaccine.
@en
P2093
P2860
P356
P1476
The microbial mimic poly IC in ...... ndritic cell targeted vaccine.
@en
P2093
Christine Trumpfheller
Godwin Nchinda
Maria Paula Longhi
Olga Mizenina
Ralph M Steinman
Sarah J Schlesinger
Yaoxing Huang
P2860
P304
P356
10.1073/PNAS.0711976105
P407
P577
2008-02-06T00:00:00Z