Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice
about
Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functionsThe role of peroxidation of mitochondrial membrane phospholipids in pancreatic β -cell failurePhospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizationsEffects of endoplasmic reticulum stress on group VIA phospholipase A2 in beta cells include tyrosine phosphorylation and increased association with calnexinGenetic ablation of PLA2G6 in mice leads to cerebellar atrophy characterized by Purkinje cell loss and glial cell activationCharacterization of FKGK18 as inhibitor of group VIA Ca2+-independent phospholipase A2 (iPLA2β): candidate drug for preventing beta-cell apoptosis and diabetesGroup VIA phospholipase A2 mitigates palmitate-induced β-cell mitochondrial injury and apoptosisGenetic ablation of calcium-independent phospholipase A2gamma prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation.Evidence for proteolytic processing and stimulated organelle redistribution of iPLA(2)beta.Group VIA Ca2+-independent phospholipase A2 (iPLA2beta) and its role in beta-cell programmed cell death.Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet.Evidence of contribution of iPLA2β-mediated events during islet β-cell apoptosis due to proinflammatory cytokines suggests a role for iPLA2β in T1D development.Therapeutic effects of a non-β cell bioartificial pancreas in diabetic mice.Platelet-activating factor and metastasis: calcium-independent phospholipase A2β deficiency protects against breast cancer metastasis to the lung.Inhibition of Ca2+-independent phospholipase A2β (iPLA2β) ameliorates islet infiltration and incidence of diabetes in NOD mice.Phospholipid hydrolysis and insulin secretion: a step toward solving the Rubik's cube.Group VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5'-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells.Mitochondrial dysfunction and β-cell failure in type 2 diabetes mellitus.Group VIA PLA2 (iPLA2β) is activated upstream of p38 mitogen-activated protein kinase (MAPK) in pancreatic islet β-cell signalingCalcium-independent phospholipases A2 and their roles in biological processes and diseases.Cytosolic and Calcium-Independent Phospholipases A2 Activation and Prostaglandins E2 Are Associated with Escherichia coli-Induced Reduction of Insulin Secretion in INS-1E Cells.Type 2 Diabetes-Associated K+ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose HomeostasisTranslational studies on regulation of brain docosahexaenoic acid (DHA) metabolism in vivo.Genetic modulation of islet β-cell iPLA₂β expression provides evidence for its impact on β-cell apoptosis and autophagyA model of action potentials and fast Ca2+ dynamics in pancreatic beta-cellsSignal integration at the level of ion channel and exocytotic function in pancreatic β-cells.A PLA1-2 punch regulates the Golgi complex.Defective lipid metabolism in neurodegeneration with brain iron accumulation (NBIA) syndromes: not only a matter of iron.Role of cytosolic and calcium independent phospholipases A(2) in insulin secretion impairment of INS-1E cells infected by S. aureus.Endothelial cell prostaglandin I(2) and platelet-activating factor production are markedly attenuated in the calcium-independent phospholipase A(2)beta knockout mouseCalcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses.High Spatial Resolution Imaging of Mouse Pancreatic Islets Using Nanospray Desorption Electrospray Ionization Mass Spectrometry.
P2860
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P2860
Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Glucose homeostasis, insulin s ...... lls and in iPLA2beta-null mice
@ast
Glucose homeostasis, insulin s ...... lls and in iPLA2beta-null mice
@en
type
label
Glucose homeostasis, insulin s ...... lls and in iPLA2beta-null mice
@ast
Glucose homeostasis, insulin s ...... lls and in iPLA2beta-null mice
@en
prefLabel
Glucose homeostasis, insulin s ...... lls and in iPLA2beta-null mice
@ast
Glucose homeostasis, insulin s ...... lls and in iPLA2beta-null mice
@en
P2093
P2860
P921
P1476
Glucose homeostasis, insulin s ...... lls and in iPLA2beta-null mice
@en
P2093
Alan Bohrer
David A Jacobson
Louis H Philipson
Mary Wohltmann
P2860
P304
P356
10.1152/AJPENDO.00474.2007
P577
2007-09-25T00:00:00Z