The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis.
about
WTH3 is a direct target of the p53 proteinNo influence of the P-glycoprotein polymorphisms MDR1 G2677T/A and C3435T on the virological and immunological response in treatment naïve HIV-positive patientsSignificance of MDR1 and multiple drug resistance in refractory human epileptic brainThe histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen speciesCross-talk between signalling pathways and the multidrug resistant protein MDR-1MRP1 gene expression level regulates the death and differentiation response of neuroblastoma cellsMDR1 causes resistance to the antitumour drug miltefosineUp-regulation of multidrug resistance P-glycoprotein via nuclear factor-kappaB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosisMethylation of WTH3, a possible drug resistant gene, inhibits p53 regulated expressionRNA helicase A in the MEF1 transcription factor complex up-regulates the MDR1 gene in multidrug-resistant cancer cells.The drug resistance proteins, multidrug resistance-associated protein and P-glycoprotein, do not confer resistance to Fas-induced cell death.Development and function of the human fetal adrenal cortex: a key component in the feto-placental unit.Anthracenedione derivatives as anticancer agents isolated from secondary metabolites of the mangrove endophytic fungiDifferential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenolsOral cyclosporin A inhibits CD4 T cell P-glycoprotein activity in HIV-infected adults initiating treatment with nucleoside reverse transcriptase inhibitorsABCB1/MDR1 gene polymorphisms as a prognostic factor in colorectal cancer.P-glycoprotein in acute myeloid leukaemia: therapeutic implications of its association with both a multidrug-resistant and an apoptosis-resistant phenotype.Multidrug transporters in prokaryotic and eukaryotic cells: physiological functions and transport mechanisms.Quantitative proteomics analysis identifies mitochondria as therapeutic targets of multidrug-resistance in ovarian cancer.JNK1-dependent antimitotic activity of thiazolidin compounds in human non-small-cell lung and colon cancer cells.Pharmacogenomics of MDR1/ABCB1 gene: the influence on risk and clinical outcome of haematological malignancies.The role of drug efflux pumps in acute myeloid leukemia.Gene therapy to protect haematopoietic cells from cytotoxic cancer drugs.ATP-binding cassette efflux transporters in human placenta.Cancer stem cells and side population cells in breast cancer and metastasis.P-glycoprotein is not involved in pathway of anti-Fas/Fas-induced apoptosis in KBv200 cells.TLR signaling modulates side effects of anticancer therapy in the small intestine.Pharmacogenetics of MDR1 and its impact on the pharmacokinetics and pharmacodynamics of drugs.Engineering polymeric aptamers for selective cytotoxicity.Identification and characterization of the binding sites of P-glycoprotein for multidrug resistance-related drugs and modulators.MYCN enhances P-gp/MDR1 gene expression in the human metastatic neuroblastoma IGR-N-91 model.Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation.Strategies for overcoming p-glycoprotein-mediated drug resistance in acute myeloblastic leukaemia.Reversing multidrug resistance in breast cancer cells by silencing ABC transporter genes with nanoparticle-facilitated delivery of target siRNAs.Dasatinib reverses the multidrug resistance of breast cancer MCF-7 cells to doxorubicin by downregulating P-gp expression via inhibiting the activation of ERK signaling pathway.Suppression of P-gp induced multiple drug resistance in a drug resistant gastric cancer cell line by overexpression of FasAnti-Cripto Mab inhibit tumour growth and overcome MDR in a human leukaemia MDR cell line by inhibition of Akt and activation of JNK/SAPK and bad death pathways.Multifactorial nature of hepatocellular carcinoma drug resistance: could plant polyphenols be helpful?A role for ABCG2 beyond drug transport: Regulation of autophagy.Targeting cancer stem cells.
P2860
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P2860
The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
The drug efflux protein, P-gly ...... f caspase-dependent apoptosis.
@ast
The drug efflux protein, P-gly ...... f caspase-dependent apoptosis.
@en
type
label
The drug efflux protein, P-gly ...... f caspase-dependent apoptosis.
@ast
The drug efflux protein, P-gly ...... f caspase-dependent apoptosis.
@en
prefLabel
The drug efflux protein, P-gly ...... f caspase-dependent apoptosis.
@ast
The drug efflux protein, P-gly ...... f caspase-dependent apoptosis.
@en
P2093
P2860
P356
P1476
The drug efflux protein, P-gly ...... f caspase-dependent apoptosis.
@en
P2093
Johnstone RW
Krasovskis E
P2860
P304
P356
10.1073/PNAS.95.12.7024
P407
P577
1998-06-01T00:00:00Z