Cross-linking of cell surface amyloid precursor protein leads to increased β-amyloid peptide production in hippocampal neurons: implications for Alzheimer's disease.
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Diabetes Mellitus Induces Alzheimer's Disease Pathology: Histopathological Evidence from Animal ModelsAmyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's diseaseThe multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foesArf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomesAssembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progressionCaspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice.Amyloid-β Peptide Exacerbates the Memory Deficit Caused by Amyloid Precursor Protein Loss-of-Function in Drosophila.Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.Soluble amyloid precursor protein alpha inhibits tau phosphorylation through modulation of GSK3β signaling pathway.β-Secretase: its biology as a therapeutic target in diseasesAutophagy-mediated Regulation of BACE1 Protein Trafficking and Degradation.Retromer and Rab2-dependent trafficking mediate PS1 degradation by proteasomes in endocytic disturbance.Amyloid Precursor Protein family as unconventional Go-coupled receptors and the control of neuronal motility.Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.Snapin-mediated BACE1 retrograde transport is essential for its degradation in lysosomes and regulation of APP processing in neurons.Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ1-42 synaptotoxicity.Low-Density Lipoprotein Receptor-Related Protein-1 (LRP1) C4408R Mutant Promotes Amyloid Precursor Protein (APP) α-Cleavage in Vitro.BACE1 SUMOylation increases its stability and escalates the protease activity in Alzheimer's disease.
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P2860
Cross-linking of cell surface amyloid precursor protein leads to increased β-amyloid peptide production in hippocampal neurons: implications for Alzheimer's disease.
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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name
Cross-linking of cell surface ...... tions for Alzheimer's disease.
@ast
Cross-linking of cell surface ...... tions for Alzheimer's disease.
@en
type
label
Cross-linking of cell surface ...... tions for Alzheimer's disease.
@ast
Cross-linking of cell surface ...... tions for Alzheimer's disease.
@en
prefLabel
Cross-linking of cell surface ...... tions for Alzheimer's disease.
@ast
Cross-linking of cell surface ...... tions for Alzheimer's disease.
@en
P2093
P2860
P1476
Cross-linking of cell surface ...... tions for Alzheimer's disease.
@en
P2093
Julio Pozueta
Michael Shelanski
Roger Lefort
P2860
P304
10674-10685
P356
10.1523/JNEUROSCI.6473-11.2012
P407
P577
2012-08-01T00:00:00Z