Delineation of an extended surface contact area on human CD4 involved in class II major histocompatibility complex binding
about
Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC moleculeCharacterization of the major histocompatibility complex class II binding site on LAG-3 proteinHLA-DR polymorphism affects the interaction with CD4Immune checkpoint blockade: a common denominator approach to cancer therapyThe CD58 (LFA-3) binding site is a localized and highly charged surface area on the AGFCC'C" face of the human CD2 adhesion domain.Association of the porcine cluster of differentiation 4 gene with T lymphocyte subpopulations and its expression in immune tissuesEngineered single human CD4 domains as potent HIV-1 inhibitors and components of vaccine immunogensOligomerization of CD4 is required for stable binding to class II major histocompatibility complex proteins but not for interaction with human immunodeficiency virus gp120.Analysis of the binding site on intercellular adhesion molecule 3 for the leukocyte integrin lymphocyte function-associated antigen 1.Modulation of CD4 T cell function by soluble MHC II-peptide chimeras.Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice.Involvement of both major histocompatibility complex class II alpha and beta chains in CD4 function indicates a role for ordered oligomerization in T cell activationLAG-3 in Cancer Immunotherapy.The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection.Biallelic, ubiquitous transcription from the distal germline Ig{kappa} locus promoter during B cell development.Co-receptors and recognition of self at the immunological synapse.Critical factors in basal cell adhesion molecule/lutheran-mediated adhesion to laminin.LAG3 (CD223) as a cancer immunotherapy target.Efficient CD4 binding and immunosuppressive properties of the 13B8.2 monoclonal antibody are displayed by its CDR-H1-derived peptide CB1.Identification of a human CD4-CDR3-like surface involved in CD4+ T cell function.Immunoglobulin superfamily proteins: structure, mechanisms, and drug discovery.T Cell Receptor Binding to a pMHCII Ligand Is Kinetically Distinct from and Independent of CD4.A5, a new small-molecule inhibitor of CD4 D1 obtained from a computer-aided screening method, contributes to the inhibition of CD4+ T-cell function.Transduction of Activation Signal That Follows HIV-1 Binding to CD4 and CD4 Dimerization Involves the Immunoglobulin CDR3-like Region in Domain 1 of CD4
P2860
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P2860
Delineation of an extended surface contact area on human CD4 involved in class II major histocompatibility complex binding
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Delineation of an extended sur ...... ocompatibility complex binding
@ast
Delineation of an extended sur ...... ocompatibility complex binding
@en
type
label
Delineation of an extended sur ...... ocompatibility complex binding
@ast
Delineation of an extended sur ...... ocompatibility complex binding
@en
prefLabel
Delineation of an extended sur ...... ocompatibility complex binding
@ast
Delineation of an extended sur ...... ocompatibility complex binding
@en
P2093
P2860
P356
P1476
Delineation of an extended sur ...... ocompatibility complex binding
@en
P2093
E L Reinherz
S C Harrison
P2860
P304
P356
10.1073/PNAS.90.17.8259
P407
P577
1993-09-01T00:00:00Z