Expression of SV-40 T antigen in the small intestinal epithelium of transgenic mice results in proliferative changes in the crypt and reentry of villus-associated enterocytes into the cell cycle but has no apparent effect on cellular differentiation
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Fibroblast growth factor receptor-3 regulates Paneth cell lineage allocation and accrual of epithelial stem cells during murine intestinal development.Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergenceCell proliferation in gastrointestinal mucosa.Intestinal dysplasia induced by simian virus 40 T antigen is independent of p53.Novel insights into human intestinal epithelial cell proliferation in health and disease using confocal microscopy.Epithelial cell proliferation in childhood enteropathies.Transforming functions of Simian Virus 40.Doublecortin and CaM kinase-like-1 and leucine-rich-repeat-containing G-protein-coupled receptor mark quiescent and cycling intestinal stem cells, respectively.Expression of wild-type and mutant simian virus 40 large tumor antigens in villus-associated enterocytes of transgenic mice.Enterocyte proliferation and intestinal hyperplasia induced by simian virus 40 T antigen require a functional J domainIntestinal hyperplasia induced by simian virus 40 large tumor antigen requires E2F2.Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia.Use of transgenic mice to map cis-acting elements in the intestinal fatty acid binding protein gene (Fabpi) that control its cell lineage-specific and regional patterns of expression along the duodenal-colonic and crypt-villus axes of the gut epitheCell lineage-specific and differentiation-dependent patterns of CCAAT/enhancer binding protein alpha expression in the gut epithelium of normal and transgenic mice.Cell-type specific regulation of gene expression by simian virus 40 T antigens.Simian virus 40 T-antigen-mediated gene regulation in enterocytes is controlled primarily by the Rb-E2F pathwayCrypt stem cell survival in the mouse intestinal epithelium is regulated by prostaglandins synthesized through cyclooxygenase-1.T antigen transgenic mouse modelsGenetic engineering of carbohydrate biosynthetic pathways in transgenic mice demonstrates cell cycle-associated regulation of glycoconjugate production in small intestinal epithelial cells.Transgenic Mouse Models of SV40-Induced Cancer.Genetic regulation of enterocyte differentiation.Growth control mechanisms in normal and transformed intestinal cellsEnterocyte differentiation is compatible with SV40 large T expression and loss of p53 function in human colonic Caco-2 cells. Status of the pRb1 and pRb2 tumor suppressor gene products.Retinoblastoma protein (pRb), but not p107 or p130, is required for maintenance of enterocyte quiescence and differentiation in small intestine.Temporal differentiation and migration of substance P, serotonin, and secretin immunoreactive enteroendocrine cells in the mouse proximal small intestine.Simian virus 40 T antigen-induced amplification of pre-parietal cells in transgenic mice. Effects on other gastric epithelial cell lineages and evidence for a p53-independent apoptotic mechanism that operates in a committed progenitor.Characterization of mouse A33 antigen, a definitive marker for basolateral surfaces of intestinal epithelial cells.Sepsis reveals compartment-specific responses in intestinal proliferation and apoptosis in transgenic mice whose enterocytes re-enter the cell cycle.Molecular mechanisms of enteroendocrine differentiation.Disruption of cyclooxygenase-1 gene results in an impaired response to radiation injury.The related retinoblastoma (pRb) and p130 proteins cooperate to regulate homeostasis in the intestinal epithelium.
P2860
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P2860
Expression of SV-40 T antigen in the small intestinal epithelium of transgenic mice results in proliferative changes in the crypt and reentry of villus-associated enterocytes into the cell cycle but has no apparent effect on cellular differentiation
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Expression of SV-40 T antigen ...... ct on cellular differentiation
@ast
Expression of SV-40 T antigen ...... ct on cellular differentiation
@en
type
label
Expression of SV-40 T antigen ...... ct on cellular differentiation
@ast
Expression of SV-40 T antigen ...... ct on cellular differentiation
@en
prefLabel
Expression of SV-40 T antigen ...... ct on cellular differentiation
@ast
Expression of SV-40 T antigen ...... ct on cellular differentiation
@en
P2093
P2860
P356
P1476
Expression of SV-40 T antigen ...... ct on cellular differentiation
@en
P2093
G H Schmidt
J R Hansbrough
P2860
P304
P356
10.1083/JCB.117.4.825
P407
P577
1992-05-01T00:00:00Z