Phosphoinositide 3-kinases p110alpha and p110beta regulate cell cycle entry, exhibiting distinct activation kinetics in G1 phase.
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Nuclear PI3K signaling in cell growth and tumorigenesisPhosphoinositide 3-kinase p85beta regulates invadopodium formation.Nuclear phosphoinositide 3-kinase beta controls double-strand break DNA repair.Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis.Comprehensive identification of mutational cancer driver genes across 12 tumor types.MYC and the control of DNA replication.Activity of any class IA PI3K isoform can sustain cell proliferation and survival.Myc proteins as therapeutic targets.Downregulation of PI3Kcb utilizing adenovirus-mediated transfer of siRNA attenuates bone cancer pain.Nuclear but not cytosolic phosphoinositide 3-kinase beta has an essential function in cell survivalRole of phosphoinositide 3-OH kinase p110β in skeletal myogenesisThe phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL.Specific function of phosphoinositide 3-kinase beta in the control of DNA replication.Targeting the PI3K pathway for cancer therapy.The nuclear localization of γ-tubulin is regulated by SadB-mediated phosphorylation.Characterization of a novel p110β-specific inhibitor BL140 that overcomes MDV3100-resistance in castration-resistant prostate cancer cells.A polybasic motif in ErbB3-binding protein 1 (EBP1) has key functions in nucleolar localization and polyphosphoinositide interactionInhibition of class IA PI3K enzymes in non-small cell lung cancer cells uncovers functional compensation among isoforms.p110α and p110β isoforms of PI3K signaling: are they two sides of the same coin?Cell activation-induced phosphoinositide 3-kinase alpha/beta dimerization regulates PTEN activity.The secret life of kinases: functions beyond catalysisPhosphoinositide 3-kinase beta controls replication factor C assembly and function.Down-regulation of p110β expression increases chemosensitivity of colon cancer cell lines to oxaliplatin.Phosphoinositide-3-kinases p110α and p110β mediate S phase entry in astroglial cells in the marginal zone of rat neocortex.Phosphoinositide 3-kinase beta protects nuclear envelope integrity by controlling RCC1 localization and Ran activity.Endometrial cancer cells exhibit high expression of p110β and its selective inhibition induces variable responses on PI3K signaling, cell survival and proliferation.Effects of PI3K catalytic subunit and Akt isoform deficiency on mTOR and p70S6K activation in myoblastsDetermination of The Properties of Rat Brain Thermostable Protein Complex which Inhibit Cell Proliferation.Dynamics of GFP-Fusion p110α and p110β Isoforms of PI3K Signaling Pathway in Normal and Cancer Cells.
P2860
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P2860
Phosphoinositide 3-kinases p110alpha and p110beta regulate cell cycle entry, exhibiting distinct activation kinetics in G1 phase.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Phosphoinositide 3-kinases p11 ...... tivation kinetics in G1 phase.
@ast
Phosphoinositide 3-kinases p11 ...... tivation kinetics in G1 phase.
@en
type
label
Phosphoinositide 3-kinases p11 ...... tivation kinetics in G1 phase.
@ast
Phosphoinositide 3-kinases p11 ...... tivation kinetics in G1 phase.
@en
prefLabel
Phosphoinositide 3-kinases p11 ...... tivation kinetics in G1 phase.
@ast
Phosphoinositide 3-kinases p11 ...... tivation kinetics in G1 phase.
@en
P2093
P2860
P50
P356
P1476
Phosphoinositide 3-kinases p11 ...... tivation kinetics in G1 phase.
@en
P2093
Ana Gonzalez-García
Carmen Hernández
Isabel Cortés
M Carmen Moreno-Ortiz
P2860
P304
P356
10.1128/MCB.01786-07
P407
P577
2008-02-19T00:00:00Z