Effect of β,γ-CHF- and β,γ-CHCl-dGTP halogen atom stereochemistry on the transition state of DNA polymerase β.
about
On the observation of discrete fluorine NMR spectra for uridine 5'-β,γ-fluoromethylenetriphosphate diastereomers at basic pH.Quantum mechanical analysis of nonenzymatic nucleotidyl transfer reactions: kinetic and thermodynamic effects of β-γ bridging groups of dNTP substratesA Change in the Rate-Determining Step of Polymerization by the K289M DNA Polymerase β Cancer-Associated VariantFunctional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitution5'-β,γ-CHF-ATP diastereomers: synthesis and fluorine-mediated selective binding by c-Src protein kinase.Transition state in DNA polymerase β catalysis: rate-limiting chemistry altered by base-pair configuration.Remarkably Stereospecific Utilization of ATP α,β-Halomethylene Analogues by Protein Kinases.mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translationModulating the DNA polymerase β reaction equilibrium to dissect the reverse reaction.
P2860
Q33761599-D2D4F2F9-746D-40B8-BFB9-7BCD5E17124FQ33843012-907DD8C4-A713-4301-8B0B-9F70CA5F1668Q33923598-B7DDC012-C684-4251-B67E-A67EF0A0C494Q36870576-D5951196-1E5A-4597-A116-DE22973F0C36Q36966447-FBB2B6F1-912F-4E65-A70D-3D14577B4556Q37701454-854D1C71-08D7-486C-B67F-8FA0565B539BQ40189472-3EAB893D-3291-4802-ADE3-3246C7305AE6Q41630115-6AE9F304-4CA3-4841-9AE3-9BA856958751Q50256822-CB346D2A-ACC6-448E-A39B-471E00B34A95
P2860
Effect of β,γ-CHF- and β,γ-CHCl-dGTP halogen atom stereochemistry on the transition state of DNA polymerase β.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Effect of β,γ-CHF- and β,γ-CHC ...... ion state of DNA polymerase β.
@ast
Effect of β,γ-CHF- and β,γ-CHC ...... ion state of DNA polymerase β.
@en
type
label
Effect of β,γ-CHF- and β,γ-CHC ...... ion state of DNA polymerase β.
@ast
Effect of β,γ-CHF- and β,γ-CHC ...... ion state of DNA polymerase β.
@en
prefLabel
Effect of β,γ-CHF- and β,γ-CHC ...... ion state of DNA polymerase β.
@ast
Effect of β,γ-CHF- and β,γ-CHC ...... ion state of DNA polymerase β.
@en
P2093
P2860
P356
P1433
P1476
Effect of β,γ-CHF- and β,γ-CHC ...... tion state of DNA polymerase β
@en
P2093
Boris A Kashemirov
Charles E McKenna
David D Shock
Keriann Oertell
Myron F Goodman
Valeria M Zakharova
William A Beard
P2860
P304
P356
10.1021/BI3010335
P407
P577
2012-10-19T00:00:00Z