Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice.
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Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival.FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and GNEAT1 regulates pancreatic cancer cell growth, invasion and migration though mircroRNA-335-5p/c-met axis.Jagged 1 is a major Notch ligand along cholangiocarcinoma development in mice and humans.PPARs and Mitochondrial Metabolism: From NAFLD to HCC.TIP30 regulates lipid metabolism in hepatocellular carcinoma by regulating SREBP1 through the Akt/mTOR signaling pathway.Long noncoding RNA NEAT1 promotes cell proliferation and invasion by regulating hnRNP A2 expression in hepatocellular carcinoma cells.Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma.An indispensable role of CPT-1a to survive cancer cells during energy stress through rewiring cancer metabolism.MicroRNA-206 Prevents the Pathogenesis of Hepatocellular Carcinoma Via Modulating Expression of cMet and Cdk6.Functional evaluation of synthetic flavonoids and chalcones for potential antiviral and anticancer properties.Dual inhibition of Akt and c-Met as a second-line therapy following acquired resistance to sorafenib in hepatocellular carcinoma cells.Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis.A phosphokinome-based screen uncovers new drug synergies for cancer driven by liver-specific gain of nononcogenic receptor tyrosine kinases.Hippo cascade controls lineage commitment of liver tumors in mice and humans.Loss of Pten synergizes with c-Met to promote hepatocellular carcinoma development via mTORC2 pathway.Epistructured catechins, EGCG and EC facilitate apoptosis induction through targeting de novo lipogenesis pathway in HepG2 cells.FoxM1 promotes epithelial-mesenchymal transition, invasion, and migration of tongue squamous cell carcinoma cells through a c-Met/AKT-dependent positive feedback loop.Role of Glypican-3 in the growth, migration and invasion of primary hepatocytes isolated from patients with hepatocellular carcinoma.Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice.Role of hepatoma-derived growth factor in promoting de novo lipogenesis and tumorigenesis in hepatocellular carcinoma
P2860
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P2860
Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Co-activation of AKT and c-Met ...... e mTORC1/FASN pathway in mice.
@ast
Co-activation of AKT and c-Met ...... e mTORC1/FASN pathway in mice.
@en
type
label
Co-activation of AKT and c-Met ...... e mTORC1/FASN pathway in mice.
@ast
Co-activation of AKT and c-Met ...... e mTORC1/FASN pathway in mice.
@en
prefLabel
Co-activation of AKT and c-Met ...... e mTORC1/FASN pathway in mice.
@ast
Co-activation of AKT and c-Met ...... e mTORC1/FASN pathway in mice.
@en
P2093
P2860
P356
P1433
P1476
Co-activation of AKT and c-Met ...... he mTORC1/FASN pathway in mice
@en
P2093
Diego F Calvisi
Frank Dombrowski
Guohua Zheng
Maria G Pilo
Marta Mela
Matthias Evert
Silvia Ribback
P2860
P2888
P356
10.1038/SREP20484
P407
P577
2016-02-09T00:00:00Z