Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation.
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityHuman Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysisHuman immunodeficiency virus type 1 Nef binds to tumor suppressor p53 and protects cells against p53-mediated apoptosis.hSSB1 binds and protects p21 from ubiquitin-mediated degradation and positively correlates with p21 in human hepatocellular carcinomasDifferential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosisAssociation of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathwayNegative regulation of cell growth and differentiation by TSG101 through association with p21(Cip1/WAF1).A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasomeThe bacterial redox protein azurin induces apoptosis in J774 macrophages through complex formation and stabilization of the tumor suppressor protein p53.Supramolecular complex formation between Rad6 and proteins of the p53 pathway during DNA damage-induced responseN-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasomeLovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductaseSuppression of cell transformation by the cyclin-dependent kinase inhibitor p57KIP2 requires binding to proliferating cell nuclear antigenInvestigations of methylmercury-induced alterations in neurogenesisAn N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivoIFI16 as a negative regulator in the regulation of p53 and p21(Waf1)Effects of histone acetylation and DNA methylation on p21( WAF1) regulationRole of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damageTwo 4N cell-cycle arrests contribute to cisplatin-resistanceThe novel tubulin polymerization inhibitor MHPT exhibits selective anti-tumor activity against rhabdomyosarcoma in vitro and in vivop53-mediated regulation of proliferating cell nuclear antigen expression in cells exposed to ionizing radiationOligomerization is required for p53 to be efficiently ubiquitinated by MDM2Cleavage of p21/WAF1/CIP1 by proteinase 3 modulates differentiation of a monocytic cell line. Molecular analysis of the cleavage site.Polycyclic aromatic hydrocarbon carcinogens increase ubiquitination of p21 protein after the stabilization of p53 and the expression of p21.Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents.Over-expression of ubiquitin carboxy terminal hydrolase-L1 induces apoptosis in breast cancer cells.Oct-4 controls cell-cycle progression of embryonic stem cells.Mdm2 facilitates the association of p53 with the proteasome.Adenovirus E1A-regulated transcription factor p120E4F inhibits cell growth and induces the stabilization of the cdk inhibitor p21WAF1.Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stressRegulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation.Ubiquitin-mediated proteolysis of vertebrate G1- and S-phase regulators.Hypophosphorylation of Mdm2 augments p53 stabilityMechanism of p53 stabilization by ATM after DNA damage.Hypoxia links ATR and p53 through replication arrest.MAP/ERK kinase kinase 1 (MEKK1) mediates transcriptional repression by interacting with polycystic kidney disease-1 (PKD1) promoter-bound p53 tumor suppressor proteinAntitumor effects of tyropeptin-boronic acid derivatives: New proteasome inhibitors.RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiationP53 and p73 differ in their ability to inhibit glucocorticoid receptor (GR) transcriptional activity.The p53-Mdm2 association in epithelial cells in idiopathic pulmonary fibrosis and non-specific interstitial pneumonia.
P2860
Q21263027-836069CE-D07E-4B53-B4B9-C4D7357771ECQ22010136-539AD57D-1B1B-40E1-960B-AD023F007FFCQ24292352-EAF310C6-1A23-4444-A99A-FE6170E8961CQ24337430-63175814-104C-4AAA-8EAE-5D44BAB7A1ADQ24338676-54780F5B-344F-442E-AE15-75576D8FE945Q24532945-237E6A8B-DEB0-4734-AF81-6D11C1B10F5EQ24534132-A7DE84D8-2D32-4A16-9D8D-C0BF56C84D85Q24535198-B318338A-AF1C-474F-A3FC-294237E14EB3Q24536176-FDCBCC13-6AAB-49C2-8D23-D6582A0294F0Q24551106-9C1B1471-8081-4365-9784-E92E1EEEA6AFQ24563960-BA4B0680-2892-499D-96FE-E445B8DB2C68Q24645348-70FC6A41-2550-4CCB-89C3-9882B1E7CD91Q24682776-5B19D4A5-8786-4B60-80C0-4028E53AD78CQ24812651-953994B2-80F7-48A5-9EA2-D89BEA6F1F2FQ28144965-B8B27B7E-7F3E-4E34-A5EA-B12BCBF599BFQ28202318-66EFDD21-A1FA-460D-B37F-7965D44C5C6FQ28202424-722EB91F-A24F-4CD7-AA9D-1C15EE6ABBFEQ28208518-F3B0D029-7B1E-4FFD-AA04-83C23A31A59AQ28485896-F1C18981-AC32-4803-9798-23F4BB41F2C3Q28545041-BD55D200-EB79-40BA-B547-D1E360D0527CQ28609219-85589DF2-C455-4D38-B722-005A63D3CCD5Q28609844-5E430DF6-67B2-42B8-965E-4B93C060D0DDQ30855520-5759BA54-4C39-48F7-A652-FBC08AD2544CQ31389933-35B98316-DAA7-4D4E-8A36-2A2CEC94246CQ32062474-71B37EEF-C250-4BE6-B4C4-45D8D7505E4DQ33379134-AB63CC3A-18D4-4D5D-A856-14977AF44865Q33675089-CDB65CE1-4E9F-4056-8877-2C89F749ACEFQ33933283-D72D4458-2183-4BB8-887A-9B8B29A0CDA5Q33997169-3B37C77F-B0AE-4F57-8DE5-3AE30E633C02Q33997846-4B755765-ED5C-4586-AB7B-F1D7FE0B0878Q34011633-4CA4B491-9792-4540-BB5F-ABF4905751D0Q34176430-1018A4AF-6C67-4854-B78D-7F531EDC5ACCQ34285604-D2A5FEE8-3A8F-4B2E-BD4C-971FD7C0191BQ34296531-96D3E4BC-8F87-4A4B-8A32-82B0AFC70C80Q34324309-C7A8FE61-CEA8-445C-971E-D4AC09291B0DQ34386033-AE9EBBB9-7FDB-4909-B7CF-676E703EC6EBQ35052044-533C7B7D-5A23-42CD-839E-B95E4981994EQ35168095-BAB5BFFA-38BC-4F78-82FE-4C1B59E6E09CQ35250855-26965927-2AA5-436B-9CBA-6F28DC0125A7Q35588653-67FD2A93-2F33-4239-AB60-DF0C07B6C87C
P2860
Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation.
@ast
Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation.
@en
type
label
Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation.
@ast
Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation.
@en
prefLabel
Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation.
@ast
Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation.
@en
P2860
P356
P1476
Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation.
@en
P2093
P2860
P304
P356
10.1128/MCB.17.1.355
P407
P577
1997-01-01T00:00:00Z