DAX-1 inhibits SF-1-mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita.
about
Orphan receptor DAX-1 is a shuttling RNA binding protein associated with polyribosomes via mRNARepressors of androgen and progesterone receptor actionWnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergyThe orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repressionA novel mutation in DAX1 causes delayed-onset adrenal insufficiency and incomplete hypogonadotropic hypogonadismSF-1 a key player in the development and differentiation of steroidogenic tissuesNew clues to the puzzle of mammalian sex determinationFunctional Zonation of the Adult Mammalian Adrenal CortexImpact of ACTH Signaling on Transcriptional Regulation of Steroidogenic GenesDAX-1 (NR0B1) and steroidogenic factor-1 (SF-1, NR5A1) in human diseaseThe structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1Interaction of the corepressor Alien with DAX-1 is abrogated by mutations of DAX-1 involved in adrenal hypoplasia congenitaModulation of human luteinizing hormone beta gene transcription by MIP-2AFunction of the transcriptional regulating protein of 132 kDa (TReP-132) on human P450scc gene expressionSmall heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivationDax1 antagonizes Sry action in mammalian sex determinationDEAD-box protein-103 (DP103, Ddx20) is essential for early embryonic development and modulates ovarian morphology and functionSynergy of SF1 and RAR in activation of Oct-3/4 promoterDax1 associates with Esrrb and regulates its function in embryonic stem cellsTruncated estrogen receptor product-1 suppresses estrogen receptor transactivation by dimerization with estrogen receptors alpha and beta.Steroidogenic factor-1 (SF-1)-driven differentiation of murine embryonic stem (ES) cells into a gonadal lineageStructure and expression of the orphan nuclear receptor SHP gene.Developmental expression of DAX1 in the European sea bass, Dicentrarchus labrax: lack of evidence for sexual dimorphism during sex differentiationCBP/p300-interacting transactivator, with Glu/Asp-rich C-terminal domain, 2, and pre-B-cell leukemia transcription factor 1 in human adrenal development and disease.Minireview: steroidogenic factor 1: its roles in differentiation, development, and diseaseNew solutions to an ancient riddle: defining the differences between Adam and Eve.Progenitor cell expansion and organ size of mouse adrenal is regulated by sonic hedgehogNuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1Sex determination and the Y chromosome.Susceptible periods during embryogenesis of the heart and endocrine glandsSRY interacts with and negatively regulates androgen receptor transcriptional activity.The Wilms' tumor suppressor gene (wt1) product regulates Dax-1 gene expression during gonadal differentiation.X-linked adrenal hypoplasia congenita is caused by abnormal nuclear localization of the DAX-1 protein.Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner.SF-1 (nuclear receptor 5A1) activity is activated by cyclic AMP via p300-mediated recruitment to active foci, acetylation, and increased DNA binding.Transcription factors as regulators of steroidogenic P-450 enzymes.Sex determination: lessons from families and embryos.Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism.Regulation of male sexual development by Sry and Sox9.DAX1 mutations map to putative structural domains in a deduced three-dimensional model.
P2860
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P2860
DAX-1 inhibits SF-1-mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
DAX-1 inhibits SF-1-mediated t ...... adrenal hypoplasia congenita.
@ast
DAX-1 inhibits SF-1-mediated t ...... adrenal hypoplasia congenita.
@en
type
label
DAX-1 inhibits SF-1-mediated t ...... adrenal hypoplasia congenita.
@ast
DAX-1 inhibits SF-1-mediated t ...... adrenal hypoplasia congenita.
@en
prefLabel
DAX-1 inhibits SF-1-mediated t ...... adrenal hypoplasia congenita.
@ast
DAX-1 inhibits SF-1-mediated t ...... adrenal hypoplasia congenita.
@en
P2093
P2860
P356
P1476
DAX-1 inhibits SF-1-mediated t ...... adrenal hypoplasia congenita.
@en
P2093
P2860
P304
P356
10.1128/MCB.17.3.1476
P407
P577
1997-03-01T00:00:00Z