Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndrome
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Cellular Senescence:Ex Vivop53-Dependent Asymmetric Cell KineticsMyc activates telomeraseCDDO-Me protects normal lung and breast epithelial cells but not cancer cells from radiationMolecular and anatomic considerations in the pathogenesis of breast cancer.Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells.Phenotypic plasticity in normal breast derived epithelial cells.p53 modulates Hsp90 ATPase activity and regulates aryl hydrocarbon receptor signaling.Structural cues from the tissue microenvironment are essential determinants of the human mammary epithelial cell phenotype.Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristicsAlternative lengthening of telomeres in mammalian cells.An in vitro model of human breast carcinogenesis: epigenetic aspects.Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes.Li-Fraumeni syndrome--a molecular and clinical review.A molecular signature of normal breast epithelial and stromal cells from Li-Fraumeni syndrome mutation carriers.Asymmetric cell kinetics genes: the key to expansion of adult stem cells in culture.Spontaneous immortalization of mouse liver sinusoidal endothelial cellsA cancer-associated PCNA expressed in breast cancer has implications as a potential biomarker.Primed for cancer: Li Fraumeni Syndrome and the pre-cancerous nicheMutational analysis of human papillomavirus type 16 E6 demonstrates that p53 degradation is necessary for immortalization of mammary epithelial cells.A targeted RNAi screen of the breast cancer genome identifies KIF14 and TLN1 as genes that modulate docetaxel chemosensitivity in triple-negative breast cancer.Immortalization of epithelial progenitor cells mediated by resveratrol.Genotype phenotype correlation in Li-Fraumeni syndrome kindreds and its implications for management.Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblastsReprogramming of telomerase by expression of mutant telomerase RNA template in human cells leads to altered telomeres that correlate with reduced cell viabilityEffects of p53 mutations on apoptosis in mouse intestinal and human colonic adenomas.A human breast cancer model for the study of telomerase inhibitors based on a new biotinylated-primer extension assay.Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death.Li Fraumeni syndrome, cancer and senescence: a new hypothesis.Regulation of in situ to invasive breast carcinoma transitionElevated TRF2 in advanced breast cancers with short telomeres.Critical pathways in cellular senescence and immortalization revealed by gene expression profiling.LPA receptor activity is basal specific and coincident with early pregnancy and involution during mammary gland postnatal developmentp53 protein regulates Hsp90 ATPase activity and thereby Wnt signaling by modulating Aha1 expressionHsp90 and PKM2 Drive the Expression of Aromatase in Li-Fraumeni Syndrome Breast Adipose Stromal Cells.Detection of telomerase activity by combination of TRAP method and scintillation proximity assay (SPA).Telomerase immortalization of human mammary epithelial cells derived from a BRCA2 mutation carrier.Clonal heterogeneity in telomerase activity and telomere length in tumor-derived cell lines.Telomerase activation in human fibroblasts during escape from crisis.Absence of cancer-associated changes in human fibroblasts immortalized with telomerase.Characterization of paired tumor and non-tumor cell lines established from patients with breast cancer.
P2860
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P2860
Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndrome
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Spontaneous in vitro immortali ...... ient with Li-Fraumeni syndrome
@ast
Spontaneous in vitro immortali ...... ient with Li-Fraumeni syndrome
@en
type
label
Spontaneous in vitro immortali ...... ient with Li-Fraumeni syndrome
@ast
Spontaneous in vitro immortali ...... ient with Li-Fraumeni syndrome
@en
prefLabel
Spontaneous in vitro immortali ...... ient with Li-Fraumeni syndrome
@ast
Spontaneous in vitro immortali ...... ient with Li-Fraumeni syndrome
@en
P2093
P2860
P356
P1476
Spontaneous in vitro immortali ...... ient with Li-Fraumeni syndrome
@en
P2093
G Tomlinson
L S Gollahon
M A Piatyszek
P2860
P304
P356
10.1128/MCB.15.1.425
P407
P577
1995-01-01T00:00:00Z