Ligand recognition by drug-activated nuclear receptors PXR and CAR: structural, site-directed mutagenesis and molecular modeling studies.
about
Neurosteroid regulation of central nervous system developmentBiology of PXR: role in drug-hormone interactionsDEC1 binding to the proximal promoter of CYP3A4 ascribes to the downregulation of CYP3A4 expression by IL-6 in primary human hepatocytesGadd45β is an inducible coactivator of transcription that facilitates rapid liver growth in miceCAR and PXR: the xenobiotic-sensing receptors.Metabolomics reveals a novel vitamin E metabolite and attenuated vitamin E metabolism upon PXR activation.Oxazaphosphorine bioactivation and detoxification The role of xenobiotic receptors.Effect of prototypical inducers on ligand activated nuclear receptor regulated drug disposition genes in rodent hepatic and intestinal cells.In Vitro Approaches to Study Regulation of Hepatic Cytochrome P450 (CYP) 3A Expression by Paclitaxel and Rifampicin.Suppression of carboxylesterases by imatinib mediated by the down-regulation of pregnane X receptor.Characterization of ligand-dependent activation of bovine and pig constitutive androstane (CAR) and pregnane X receptors (PXR) with interspecies comparisons.
P2860
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P2860
Ligand recognition by drug-activated nuclear receptors PXR and CAR: structural, site-directed mutagenesis and molecular modeling studies.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Ligand recognition by drug-act ...... nd molecular modeling studies.
@ast
Ligand recognition by drug-act ...... nd molecular modeling studies.
@en
type
label
Ligand recognition by drug-act ...... nd molecular modeling studies.
@ast
Ligand recognition by drug-act ...... nd molecular modeling studies.
@en
prefLabel
Ligand recognition by drug-act ...... nd molecular modeling studies.
@ast
Ligand recognition by drug-act ...... nd molecular modeling studies.
@en
P1476
Ligand recognition by drug-act ...... and molecular modeling studies
@en
P2093
Antti Poso
Paavo Honkakoski
P304
P356
10.2174/138955706777935008
P577
2006-08-01T00:00:00Z