Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.
about
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signalingProtein kinase WNK2 inhibits cell proliferation by negatively modulating the activation of MEK1/ERK1/2Raf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulationc-Jun regulates cell cycle progression and apoptosis by distinct mechanismsActivation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells.Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activationRegulation of the Forkhead transcription factor AFX by Ral-dependent phosphorylation of threonines 447 and 451Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistanceOncogene Overdose: Too Much of a Bad Thing for Oncogene-Addicted Cancer CellsG-Protein-Coupled Receptors: Next Generation Therapeutic Targets in Head and Neck Cancer?Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyondMultidentate Small-Molecule Inhibitors of Vaccinia H1-Related (VHR) Phosphatase Decrease Proliferation of Cervix Cancer CellsElucidating distinct roles for NF1 in melanomagenesisNegative feedback regulation of the ERK1/2 MAPK pathwayRas-induced cellular events (review)The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiationCalmodulin binds to K-Ras, but not to H- or N-Ras, and modulates its downstream signalingExpression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational controlProtein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactionsTrihydrophobin 1 is a new negative regulator of A-Raf kinaseRaf kinases in cancer-roles and therapeutic opportunitiesThe H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescenceModelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistanceLoss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signallingStimulation of protein kinase C-dependent and -independent signaling pathways by bistratene A in intestinal epithelial cellsBRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implicationsRaf kinase inhibitory protein regulates aurora B kinase and the spindle checkpointFunctional components of basic fibroblast growth factor signaling that inhibit lung elastin gene expressionSuppression of replicative senescence by rapamycin in rodent embryonic cellsExtracellular ATP stimulates an inhibitory pathway towards growth factor-induced cRaf-1 and MEKK activation in astrocyte culturesABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responsesRabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cellsCellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)Extracellular matrix and integrin signalling: the shape of things to comeModulation of mammalian life span by the short isoform of p53.H2S-releasing nanoemulsions: a new formulation to inhibit tumor cells proliferation and improve tissue repair.p21 in cancer: intricate networks and multiple activitiesERK signaling pathway is involved in p15INK4b/p16INK4a expression and HepG2 growth inhibition triggered by TPA and Saikosaponin a.Fibroblast growth factor 2 causes G2/M cell cycle arrest in ras-driven tumor cells through a Src-dependent pathway.Roles for p21waf1/cip1 and p27kip1 during the adaptation response to massive intestinal resection.
P2860
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P2860
Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Raf-induced proliferation or c ...... th arrest mediated by p21Cip1.
@ast
Raf-induced proliferation or c ...... th arrest mediated by p21Cip1.
@en
type
label
Raf-induced proliferation or c ...... th arrest mediated by p21Cip1.
@ast
Raf-induced proliferation or c ...... th arrest mediated by p21Cip1.
@en
prefLabel
Raf-induced proliferation or c ...... th arrest mediated by p21Cip1.
@ast
Raf-induced proliferation or c ...... th arrest mediated by p21Cip1.
@en
P2093
P2860
P356
P1476
Raf-induced proliferation or c ...... th arrest mediated by p21Cip1.
@en
P2093
P2860
P304
P356
10.1128/MCB.17.9.5598
P407
P577
1997-09-01T00:00:00Z