ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses
about
LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-kappaB activationA20-binding inhibitor of nuclear factor-kappaB (NF-kappaB)-2 (ABIN-2) is an activator of inhibitor of NF-kappaB (IkappaB) kinase alpha (IKKalpha)-mediated NF-kappaB transcriptional activityTumor progression locus 2 (Tpl2) kinase as a novel therapeutic target for cancer: double-sided effects of Tpl2 on cancerA20-Binding Inhibitor of NF-κB Activation 1 is a Physiologic Inhibitor of NF-κB: A Molecular Switch for Inflammation and AutoimmunityRegulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinaseMAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomasCrosstalk in NF-κB signaling pathwaysEmergence of the A20/ABIN-mediated inhibition of NF-κB signaling via modifying the ubiquitinated proteins in a basal chordate.IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinasesA central nervous system-restricted isoform of the interleukin-1 receptor accessory protein modulates neuronal responses to interleukin-1Tumor progression locus 2 (Map3k8) is critical for host defense against Listeria monocytogenes and IL-1 beta production.High glucose predisposes gene expression and ERK phosphorylation to apoptosis and impaired glucose-stimulated insulin secretion via the cytoskeletonTumor progression locus 2 (TPL2) regulates obesity-associated inflammation and insulin resistance.Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines.Brain-specific interleukin-1 receptor accessory protein in sleep regulation.ABIN-3: a molecular basis for species divergence in interleukin-10-induced anti-inflammatory actionsA20 inactivation in ocular adnexal MALT lymphoma.p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activationCoordinate regulation of TPL-2 and NF-κB signaling in macrophages by NF-κB1 p105.Phosphorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages.IκB kinase 2 regulates TPL-2 activation of extracellular signal-regulated kinases 1 and 2 by direct phosphorylation of TPL-2 serine 400Coordinating TLR-activated signaling pathways in cells of the immune system.Differential activation of multiple signalling pathways dictates eNOS upregulation by FGF2 but not VEGF in placental artery endothelial cells.Ebola virus VP35 induces high-level production of recombinant TPL-2-ABIN-2-NF-κB1 p105 complex in co-transfected HEK-293 cellsA20: central gatekeeper in inflammation and immunity.Ubiquitin in NF-kappaB signaling.TPL-2 negatively regulates interferon-beta production in macrophages and myeloid dendritic cells.Sodium methyldithiocarbamate exerts broad inhibition of cellular signaling and expression of effector molecules of inflammation.Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.Negative regulation of NF-κB and its involvement in rheumatoid arthritis.Regulation of NF-κB by deubiquitinases.IκB kinase regulation of the TPL-2/ERK MAPK pathway.Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update.Negative regulation of human mononuclear phagocyte function.Molecular control of the NEMO family of ubiquitin-binding proteins.Receptor signaling in immune cell development and function.Linear polyubiquitin chains: a new modifier involved in NFκB activation and chronic inflammation, including dermatitis.IRAK1-independent pathways required for the interleukin-1-stimulated activation of the Tpl2 catalytic subunit and its dissociation from ABIN2.A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1β Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte.Two-sided ubiquitin binding of NF-κB essential modulator (NEMO) zinc finger unveiled by a mutation associated with anhidrotic ectodermal dysplasia with immunodeficiency syndrome.
P2860
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P2860
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses
description
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Juni 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/06/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/06/01)
@nl
наукова стаття, опублікована в червні 2006
@uk
مقالة علمية (نشرت في يونيو 2006)
@ar
name
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses
@ast
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses
@en
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses
@nl
type
label
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses
@ast
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses
@en
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses
@nl
prefLabel
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses
@ast
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses
@en
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses
@nl
P2093
P2860
P356
P1433
P1476
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses
@en
P2093
Antony Symons
Dimitris Kioussis
Frank Kaiser
Monica P. Belich
Stamatia Papoutsopoulou
Steven C. Ley
Tharsana Tharmalingham
P2860
P304
P356
10.1038/NI1334
P407
P577
2006-06-01T00:00:00Z