Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation.
about
A mini-review on Biginelli adducts with notable pharmacological propertiesContributions of academic laboratories to the discovery and development of chemical biology toolsPlasmodium falciparum encodes a single cytosolic type I Hsp40 that functionally interacts with Hsp70 and is upregulated by heat shockBinding of a small molecule at a protein-protein interface regulates the chaperone activity of hsp70-hsp40.Studies toward a library of tetrahydrofurans: click and MCR products of mono- and bis-tetrahydrofuransChemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators.Heat shock protein 70 (hsp70) as an emerging drug target.High-throughput screening identifies a bisphenol inhibitor of SV40 large T antigen ATPase activityInhibition of large T antigen ATPase activity as a potential strategy to develop anti-polyomavirus JC drugsA screen for modulators of large T antigen's ATPase activity uncovers novel inhibitors of Simian Virus 40 and BK virus replication.The conserved core enzymatic activities and the distinct dynamics of polyomavirus large T antigensChemistry and biology of multicomponent reactions.Ciprofloxacin is an inhibitor of the Mcm2-7 replicative helicase.Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen.Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities.Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparumPharmacological targeting of the Hsp70 chaperone.Targeting Cancer Stem Cells with Novel 4-(4-Substituted phenyl)-5-(3,4,5-trimethoxy/3,4-dimethoxy)-benzoyl-3,4-dihydropyrimidine-2(1H)-one/thiones.MARCKS and HSP70 interactions regulate mucin secretion by human airway epithelial cells in vitro.Enantioselective synthesis of SNAP-7941: chiral dihydropyrimidone inhibitor of MCH1-R.Proteostasis: a new therapeutic paradigm for pulmonary disease.A precursor-specific role for Hsp40/Hsc70 during tail-anchored protein integration at the endoplasmic reticulum.Synthesis and biological evaluation of some novel fused pyrazolopyrimidines as potential anticancer and antimicrobial agents.Screening for small molecule modulators of Hsp70 chaperone activity using protein aggregation suppression assays: inhibition of the plasmodial chaperone PfHsp70-1
P2860
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P2860
Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Pyrimidinone-peptoid hybrid mo ...... nction and cell proliferation.
@ast
Pyrimidinone-peptoid hybrid mo ...... nction and cell proliferation.
@en
type
label
Pyrimidinone-peptoid hybrid mo ...... nction and cell proliferation.
@ast
Pyrimidinone-peptoid hybrid mo ...... nction and cell proliferation.
@en
prefLabel
Pyrimidinone-peptoid hybrid mo ...... nction and cell proliferation.
@ast
Pyrimidinone-peptoid hybrid mo ...... nction and cell proliferation.
@en
P2093
P2860
P50
P1476
Pyrimidinone-peptoid hybrid mo ...... nction and cell proliferation.
@en
P2093
Billy W Day
Christine M Wright
David M Turner
James M Pipas
Jeffrey L Brodsky
Nora E Jameson
Stefan Werner
P2860
P304
P356
10.1016/J.BMC.2007.12.014
P407
P577
2007-12-14T00:00:00Z