TLR9 promotes tolerance by restricting survival of anergic anti-DNA B cells, yet is also required for their activation.
about
TLRs and interferons: a central paradigm in autoimmunityNucleic Acid-Sensing Receptors: Rheostats of Autoimmunity and AutoinflammationDosage of X-linked Toll-like receptor 8 determines gender differences in the development of systemic lupus erythematosus.Altered B cell signalling in autoimmunity.Active systemic lupus erythematosus is associated with a reduced cytokine production by B cells in response to TLR9 stimulation.Roles of B Cell-Intrinsic TLR Signals in Systemic Lupus Erythematosus.Unbiased modifier screen reveals that signal strength determines the regulatory role murine TLR9 plays in autoantibody production.New insights into B cell biology in systemic lupus erythematosus and Sjögren's syndromeToll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice.CD19 controls Toll-like receptor 9 responses in human B cellsContinuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells.Role of nucleic acid-sensing TLRs in diverse autoantibody specificities and anti-nuclear antibody-producing B cells.Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.Aberrant B cell selection and activation in systemic lupus erythematosus.Contributions of B cells to lupus pathogenesisChronic lymphocytic leukaemia: could immunological tolerance mechanisms be the origin of lymphoid neoplasms?Lymphocyte-based model systems for allergy research: a historic overview.Relevant genetic polymorphisms and kidney expression of Toll-like receptor (TLR)-5 and TLR-9 in lupus nephritis.TLR7/TLR9- and B Cell Receptor-Signaling Crosstalk: Promotion of Potentially Dangerous B Cells.Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent?Germinal centers and autoimmune disease in humans and mice.Mechanisms of central tolerance for B cells.Expression of Toll‑like receptors 3 and 9 in Egyptian systemic lupus erythematosus patients.TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus.Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation.Inhibiting TLR9 and other UNC93B1-dependent TLRs paradoxically increases accumulation of MYD88L265P plasmablasts in vivo.Toll-like receptor 4 and 9 expression in B-chronic lymphocytic leukemia: relationship with infections, autoimmunity and disease progression.A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens.Cell-intrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses.Mouse models of lupus: what they tell us and what they don't.Protective Role of Myeloid Cells Expressing a G-CSF Receptor Polymorphism in an Induced Model of Lupus.New application of anti-TLR monoclonal antibodies: detection, inhibition and protection.
P2860
Q27023982-3CDD15B2-07B2-4CC1-B990-352A22D8036AQ28081728-F5E1A063-2B13-4D02-853C-A971438FF7B8Q33637487-1687D072-7D31-4AE7-9C91-5BE54AAA819FQ33924642-6F030128-8E1D-4E8A-BC35-03DDFFB406CFQ34587471-E1984F02-0D25-4EB0-9766-D135078C55E0Q35813976-BF75426D-EBA4-410D-958D-56F0952489FAQ35854962-DCACF0D0-052D-44BD-A611-B43C757160DFQ36011177-3B94AF0A-5D5D-45B6-B570-95AF678D8277Q36302763-36F1AF50-AA82-4F2C-A48A-A023C078A49AQ36665253-31574ED0-13E7-40B2-839C-740091C2EC27Q36863105-84444D4E-33B4-45D5-9C96-9A7AABBC8BB0Q37059648-83B7D8C5-B0B7-439A-8EF4-D0BA68A675E9Q37730801-2520AA8D-D31C-4B66-8940-DF5EEE80B925Q38114501-19C0195D-ABDC-4FB0-8F91-CA12A37D549AQ38170793-E974030F-8E84-423E-8B30-14D21638AAD6Q38197232-B4DBB880-805D-4329-B883-C6A98042EA50Q38207877-E660ADE1-ECCA-49A0-81F8-0AF92B1B95E5Q38649480-6A47D2B8-D423-4DA2-8705-C39A029B1AFFQ38656329-BA92D87A-4EDF-4971-AC2E-2DDDD6DCC352Q38929407-C04BF203-2112-411F-95B3-C1D283020036Q38937343-B93FA6AA-A511-40C9-BC14-C4741FD45556Q39214736-651447F0-6000-4669-8245-555E7D84FC42Q39294720-4C990A93-E119-453A-A701-D6FECCACB26CQ39647280-3E4EA518-3201-4480-A5BC-028D937070EEQ40173384-0E765D95-A462-4BD0-B39A-B7B004581099Q41168768-F916A1FD-6842-4FEA-8A97-6A96EF72AF3BQ42243487-98FB2DA3-9D6F-4497-B550-8B2C9FAE5FD1Q42290162-60139FA4-AE3E-46D7-9C05-1ED5CC099C47Q43213271-CB207BF8-DAAF-4E87-A500-E6D7AD7C6563Q50224231-74438282-6D1C-4727-8A4D-A386FEC59705Q54957133-5EBD9557-09BB-483E-A603-9F0D42312616Q55493201-7E5D6422-70B1-4CE4-A81E-53BE3F6AC9E0
P2860
TLR9 promotes tolerance by restricting survival of anergic anti-DNA B cells, yet is also required for their activation.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
TLR9 promotes tolerance by res ...... required for their activation.
@ast
TLR9 promotes tolerance by res ...... required for their activation.
@en
type
label
TLR9 promotes tolerance by res ...... required for their activation.
@ast
TLR9 promotes tolerance by res ...... required for their activation.
@en
prefLabel
TLR9 promotes tolerance by res ...... required for their activation.
@ast
TLR9 promotes tolerance by res ...... required for their activation.
@en
P2093
P2860
P356
P1476
TLR9 promotes tolerance by res ...... required for their activation.
@en
P2093
Eline T Luning Prak
Jaime L Cullen
Kevin M Nickerson
Mark J Shlomchik
Sean R Christensen
Wenzhao Meng
P2860
P304
P356
10.4049/JIMMUNOL.1202115
P407
P577
2013-01-07T00:00:00Z