Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis.
about
Histone H3 lysine 56 acetylation and the response to DNA replication fork damageA novel function for the Mre11-Rad50-Xrs2 complex in base excision repair.Disruption of SUMO-targeted ubiquitin ligases Slx5-Slx8/RNF4 alters RecQ-like helicase Sgs1/BLM localization in yeast and human cells.A role for Saccharomyces cerevisiae Tpa1 protein in direct alkylation repairOxidative stress and replication-independent DNA breakage induced by arsenic in Saccharomyces cerevisiaeRAD50 is required for efficient initiation of resection and recombinational repair at random, gamma-induced double-strand break endsAlkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease.A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast.Requirements for 5'dRP/AP lyase activity in Ku.Coincident resection at both ends of random, γ-induced double-strand breaks requires MRX (MRN), Sae2 (Ctp1), and Mre11-nucleaseDamage-induced localized hypermutability.Cascades of genetic instability resulting from compromised break-induced replication.Cell biology of mitotic recombination.Differential effects of poly(ADP-ribose) polymerase inhibition on DNA break repair in human cells are revealed with Epstein-Barr virusSpecificity of the dRP/AP lyase of Ku promotes nonhomologous end joining (NHEJ) fidelity at damaged ends.Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.Mechanisms of glycosylase induced genomic instabilityEvidence for abasic site sugar phosphate-mediated cytotoxicity in alkylating agent treated Saccharomyces cerevisiaeUnderstanding the origins of UV-induced recombination through manipulation of sister chromatid cohesionClusters of Multiple Mutations: Incidence and Molecular MechanismsRecombinational repair of radiation-induced double-strand breaks occurs in the absence of extensive resection.Homologous recombination rescues ssDNA gaps generated by nucleotide excision repair and reduced translesion DNA synthesis in yeast G2 cells.Deficient SUMO attachment to Flp recombinase leads to homologous recombination-dependent hyperamplification of the yeast 2 microm circle plasmid.The transition of closely opposed lesions to double-strand breaks during long-patch base excision repair is prevented by the coordinated action of DNA polymerase delta and Rad27/Fen1.The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products.Resection activity of the Sgs1 helicase alters the affinity of DNA ends for homologous recombination proteins in Saccharomyces cerevisiae.Replication fork slowing and stalling are distinct, checkpoint-independent consequences of replicating damaged DNA.APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast.Characterizing resection at random and unique chromosome double-strand breaks and telomere ends.Multi-scale tracking reveals scale-dependent chromatin dynamics after DNA damage.DNA repair defects sensitize cells to anticodon nuclease yeast killer toxins.Flap endonuclease overexpression drives genome instability and DNA damage hypersensitivity in a PCNA-dependent manner.i-BLESS is an ultra-sensitive method for detection of DNA double-strand breaksRole of Homologous Recombination Genes in Repair of Alkylation Base Damage by
P2860
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P2860
Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Apn1 and Apn2 endonucleases pr ...... y direct chromosomal analysis.
@ast
Apn1 and Apn2 endonucleases pr ...... y direct chromosomal analysis.
@en
type
label
Apn1 and Apn2 endonucleases pr ...... y direct chromosomal analysis.
@ast
Apn1 and Apn2 endonucleases pr ...... y direct chromosomal analysis.
@en
prefLabel
Apn1 and Apn2 endonucleases pr ...... y direct chromosomal analysis.
@ast
Apn1 and Apn2 endonucleases pr ...... y direct chromosomal analysis.
@en
P2860
P356
P1476
Apn1 and Apn2 endonucleases pr ...... by direct chromosomal analysis
@en
P2093
Wenjian Ma
P2860
P304
P356
10.1093/NAR/GKM1148
P407
P577
2008-02-11T00:00:00Z