A novel F(420) -dependent anti-oxidant mechanism protects Mycobacterium tuberculosis against oxidative stress and bactericidal agents
about
Rv2074 is a novel F420 H2 -dependent biliverdin reductase in Mycobacterium tuberculosisMycobacterial F420H2-Dependent Reductases Promiscuously Reduce Diverse Compounds through a Common Mechanism.In vitro and in vivo activities of the nitroimidazole TBA-354 against Mycobacterium tuberculosisInteraction of Pattern Recognition Receptors with Mycobacterium TuberculosisThe tuberculosis drug discovery and development pipeline and emerging drug targets.Mode of Action of Clofazimine and Combination Therapy with Benzothiazinones against Mycobacterium tuberculosisMutations in genes for the F420 biosynthetic pathway and a nitroreductase enzyme are the primary resistance determinants in spontaneous in vitro-selected PA-824-resistant mutants of Mycobacterium tuberculosisPhysiology, Biochemistry, and Applications of F420- and Fo-Dependent Redox Reactions.F420H2 Is Required for Phthiocerol Dimycocerosate Synthesis in Mycobacteria.The redox cofactor F420 protects mycobacteria from diverse antimicrobial compounds and mediates a reductive detoxification system.Tuberculosis drug discovery and emerging targets.Oxidative Phosphorylation as a Target Space for Tuberculosis: Success, Caution, and Future Directions.Discovery and characterization of an F420-dependent glucose-6-phosphate dehydrogenase (Rh-FGD1) from Rhodococcus jostii RHA1.Elongation of the Poly-γ-glutamate Tail of F420 Requires Both Domains of the F420:γ-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis.The methanogenic redox cofactor F420 is widely synthesized by aerobic soil bacteria.Rational design of drug-like compounds targeting Mycobacterium marinum MelF protein.Lack of mycothiol and ergothioneine induces different protective mechanisms in Mycobacterium smegmatisProtonation state of F420H2 in the prodrug-activating deazaflavin dependent nitroreductase (Ddn) from Mycobacterium tuberculosisCitE Enzymes Are Essential for to Establish Infection in Macrophages and Guinea Pigs
P2860
Q27715540-4DF3C876-8BDD-4821-8A1D-09E7216CA6CAQ33742133-34E590D1-5844-453D-A82E-413C6E06EFA5Q34922070-D3C43A41-EC4D-4F54-B97D-7D9EA3E0842EQ35014476-0C283F45-767D-4288-BF70-B72AE3B812F0Q35664209-284EF413-3294-4D3B-B3E2-6D76907FF184Q35859964-C18436A0-33AE-4B7F-852E-A62318BA7960Q35960987-3C32B2E1-0DBE-4661-A699-8391CD482A67Q36902459-EFF044D4-82E0-40F8-9059-7801577951CBQ37093372-D8141705-3126-4B70-9287-13A15EF65290Q37405343-255E0207-2885-41EC-9774-918B2DAD1566Q38219605-9960F981-63AD-4936-8370-DDFCE2E785BBQ38672958-CE040308-8A52-4B48-BE92-028B5E9E5A87Q39103111-A302C0E0-B6BB-41A5-8CC7-E53B1AB072FBQ39483290-F7530680-B809-4C66-A630-8831021FB3C8Q39507837-7B9CF883-5A5C-40DA-B27E-7E4D3DC423D7Q40066304-FCAC6778-067E-4C81-8DC1-FD38A8CED7D8Q41682772-82766C63-876E-47F1-9C1F-F7CD8938889CQ58044101-2062D279-ABB5-40F7-9807-A6357441D3F1Q59136481-FA5E4091-26EE-4EE8-8693-502723A2A017
P2860
A novel F(420) -dependent anti-oxidant mechanism protects Mycobacterium tuberculosis against oxidative stress and bactericidal agents
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
A novel F(420) -dependent anti ...... stress and bactericidal agents
@ast
A novel F(420) -dependent anti ...... stress and bactericidal agents
@en
type
label
A novel F(420) -dependent anti ...... stress and bactericidal agents
@ast
A novel F(420) -dependent anti ...... stress and bactericidal agents
@en
prefLabel
A novel F(420) -dependent anti ...... stress and bactericidal agents
@ast
A novel F(420) -dependent anti ...... stress and bactericidal agents
@en
P2093
P2860
P50
P356
P1476
A novel F(420) -dependent anti ...... stress and bactericidal agents
@en
P2093
Helena I Boshoff
Meera Gurumurthy
Srinivasa P S Rao
Tathagata Mukherjee
Ujjini H Manjunatha
P2860
P304
P356
10.1111/MMI.12127
P407
P577
2012-12-28T00:00:00Z