Activity and regulation by growth factors of calmodulin-dependent protein kinase III (elongation factor 2-kinase) in human breast cancer.
about
Targeting translation initiation in breast cancerThe molecular mechanism of eukaryotic elongation factor 2 kinase activationCalcium/calmodulin stimulates the autophosphorylation of elongation factor 2 kinase on Thr-348 and Ser-500 to regulate its activity and calcium dependenceProteome study of colorectal carcinogenesis.Gene trap mutagenesis-based forward genetic approach reveals that the tumor suppressor OVCA1 is a component of the biosynthetic pathway of diphthamide on elongation factor 2.Cytoprotective effect of the elongation factor-2 kinase-mediated autophagy in breast cancer cells subjected to growth factor inhibition.Prediction and testing of biological networks underlying intestinal cancerAberrations in translational regulation are associated with poor prognosis in hormone receptor-positive breast cancerEukaryotic elongation factor 2 kinase regulates the development of hypertension through oxidative stress-dependent vascular inflammationNew frontiers in translational control of the cancer genomeModulation of molecular mechanisms involved in protein synthesis machinery as a new tool for the control of cell proliferation.Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancerElongation factor-2 kinase regulates TG2/β1 integrin/Src/uPAR pathway and epithelial-mesenchymal transition mediating pancreatic cancer cells invasionEukaryotic elongation factor 2 kinase activity is controlled by multiple inputs from oncogenic signalingeEF-2 kinase dictates cross-talk between autophagy and apoptosis induced by Akt Inhibition, thereby modulating cytotoxicity of novel Akt inhibitor MK-2206.Inhibition of eEF-2 kinase sensitizes human glioma cells to TRAIL and down-regulates Bcl-xL expressionPurification and characterization of tagless recombinant human elongation factor 2 kinase (eEF-2K) expressed in Escherichia coli.A high-throughput screening assay for eukaryotic elongation factor 2 kinase inhibitors.Calcium/calmodulin-dependent protein kinases as potential targets in cancer therapy.Integrated regulation of autophagy and apoptosis by EEF2K controls cellular fate and modulates the efficacy of curcumin and velcade against tumor cells.Afferent regulation of chicken auditory brainstem neurons: rapid changes in phosphorylation of elongation factor 2.Expression of elongation factor-2 kinase contributes to anoikis resistance and invasion of human glioma cellsInvestigating the kinetic mechanism of inhibition of elongation factor 2 kinase by NH125: evidence of a common in vitro artifactA critical role of eEF-2K in mediating autophagy in response to multiple cellular stresses.Serologic laboratory findings in malignancy.The role of protein synthesis in cell cycling and cancerThe alpha-kinase family: an exceptional branch on the protein kinase tree.Targeting elongation factor-2 kinase (eEF-2K) induces apoptosis in human pancreatic cancer cells.The marine polyketide myriaporone 3/4 stalls translation by targeting the elongation phase.Phosphorylation of elongation factor-2 kinase differentially regulates the enzyme's stability under stress conditions.Silencing of elongation factor-2 kinase potentiates the effect of 2-deoxy-D-glucose against human glioma cells through blunting of autophagy.Lopinavir impairs protein synthesis and induces eEF2 phosphorylation via the activation of AMP-activated protein kinase.Reversible covalent inhibition of eEF-2K by carbonitriles.Suppression of eEF-2K-mediated autophagy enhances the cytotoxicity of Raddeanin A against human breast cancer cells in vitro.eEF-2 kinase is a critical regulator of Warburg effect through controlling PP2A-A synthesis.
P2860
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P2860
Activity and regulation by growth factors of calmodulin-dependent protein kinase III (elongation factor 2-kinase) in human breast cancer.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Activity and regulation by gro ...... inase) in human breast cancer.
@ast
Activity and regulation by gro ...... inase) in human breast cancer.
@en
type
label
Activity and regulation by gro ...... inase) in human breast cancer.
@ast
Activity and regulation by gro ...... inase) in human breast cancer.
@en
prefLabel
Activity and regulation by gro ...... inase) in human breast cancer.
@ast
Activity and regulation by gro ...... inase) in human breast cancer.
@en
P2093
P2860
P356
P1476
Activity and regulation by gro ...... inase) in human breast cancer.
@en
P2093
P2860
P2888
P356
10.1038/SJ.BJC.6690012
P407
P577
1999-01-01T00:00:00Z
P5875
P6179
1027629034