Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence. - Wikidata - wikimedia - TriplyDB

Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence.

Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence.

http://www.wikidata.org/entity/Q36631943

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Emerging concepts in the immunopathogenesis of AIDS Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts Nonpathogenic simian immunodeficiency virus infections T memory stem cells and HIV: a long-term relationship Natural SIV hosts: showing AIDS the door A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo Inadequate clearance of translocated bacterial products in HIV-infected humanized mice The simian immunodeficiency virus targets central cell cycle functions through transcriptional repression in vivo Transcriptional profiling in pathogenic and non-pathogenic SIV infections reveals significant distinctions in kinetics and tissue compartmentalization Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection Kinetics of myeloid dendritic cell trafficking and activation: impact on progressive, nonprogressive and controlled SIV infections Blocking TLR7- and TLR9-mediated IFN-α production by plasmacytoid dendritic cells does not diminish immune activation in early SIV infection SIVagm infection in wild African green monkeys from South Africa: epidemiology, natural history, and evolutionary considerations Immune activation and paediatric HIV-1 disease outcome Antibiotic and Antiinflammatory Therapy Transiently Reduces Inflammation and Hypercoagulation in Acutely SIV-Infected Pigtailed Macaques Deep transcriptional sequencing of mucosal challenge compartment from rhesus macaques acutely infected with simian immunodeficiency virus implicates loss of cell adhesion preceding immune activation Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression.Going wild: lessons from naturally occurring T-lymphotropic lentiviruses Inefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infection Association of progressive CD4(+) T cell decline in SIV infection with the induction of autoreactive antibodies Paucity of CD4+ natural killer T (NKT) lymphocytes in sooty mangabeys is associated with lack of NKT cell depletion after SIV infection.Factors associated with siman immunodeficiency virus transmission in a natural African nonhuman primate host in the wild.Plasmacytoid dendritic cells accumulate and secrete interferon alpha in lymph nodes of HIV-1 patients.Rabies virus-based vaccines elicit neutralizing antibodies, poly-functional CD8+ T cell, and protect rhesus macaques from AIDS-like disease after SIV(mac251) challenge.Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections.Cycling of gut mucosal CD4+ T cells decreases after prolonged anti-retroviral therapy and is associated with plasma LPS levels.Acute mucosal pathogenesis of feline immunodeficiency virus is independent of viral dose in vaginally infected cats.Into the wild: simian immunodeficiency virus (SIV) infection in natural hosts.Pathogenic features associated with increased virulence upon Simian immunodeficiency virus cross-species transmission from natural hosts.The loss of CCR6+ and CD161+ CD4+ T-cell homeostasis contributes to disease progression in SIV-infected rhesus macaques.Th17 cells and regulatory T cells in elite control over HIV and SIV.Early microbial translocation blockade reduces SIV-mediated inflammation and viral replication.A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activation Experimental depletion of CD8+ cells in acutely SIVagm-infected African Green Monkeys results in increased viral replication.Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques.Functional cure of SIVagm infection in rhesus macaques results in complete recovery of CD4+ T cells and is reverted by CD8+ cell depletion.Immune dysregulation in human immunodeficiency virus infection: know it, fix it, prevent it?Nonprogressive and progressive primate immunodeficiency lentivirus infections.Innate immune recognition and activation during HIV infection.

P2860

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P2860

Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence.

http://www.wikidata.org/entity/Q36631943

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2007 nî lūn-bûn

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Acute loss of intestinal CD4+ ...... unodeficiency virus virulence.

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Acute loss of intestinal CD4+ ...... unodeficiency virus virulence.

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Acute loss of intestinal CD4+ ...... unodeficiency virus virulence.

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Acute loss of intestinal CD4+ ...... unodeficiency virus virulence.

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Acute loss of intestinal CD4+ ...... unodeficiency virus virulence.

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Acute loss of intestinal CD4+ ...... unodeficiency virus virulence.

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JIMMUNOL.179.5.3035

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Journal of Immunology

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Acute loss of intestinal CD4+ ...... unodeficiency virus virulence.

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Andrew A Lackner

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Daniel C Douek

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Guido Silvestri

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Isolde F Butler

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Ivona V Pandrea

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Jason M Brenchley

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Melissa Pattison

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Preston A Marx

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Rajeev Gautam

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Ronald S Veazey

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P2860

Serial human passage of simian immunodeficiency virus by unsterile injections and the emergence of epidemic human immunodeficiency virus in Africa

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes

Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif

The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

Viral dynamics in human immunodeficiency virus type 1 infection

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3035-3046

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Alan S. Perelson

Cristian Apetrei

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2007-09-01T00:00:00Z

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6129489

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17709518

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Simian immunodeficiency virus

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2367134

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