Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes
about
Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeresPOT1 association with TRF2 regulates telomere lengthTelomere elongation in immortal human cells without detectable telomerase activityVirus and host genomic, molecular, and cellular interactions during Marek's disease pathogenesis and oncogenesisA highly selective telomerase inhibitor limiting human cancer cell proliferationConditional immortalization of human B cells by CD40 ligation.Telomerase activity in normal and malignant hematopoietic cellsTelomerase enzymatic component hTERT shortens long telomeres in human cells.Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristicsCrosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.Robust activation of the human but not mouse telomerase gene during the induction of pluripotency.Molecular virology of Epstein-Barr virus.Developmental and tissue-specific regulation of mouse telomerase and telomere length.A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere statusTelomere length regulation during postnatal development and ageing in Mus spretus.Lymphomas differ in their dependence on Epstein-Barr virusThe yeast TEL1 gene partially substitutes for human ATM in suppressing hyperrecombination, radiation-induced apoptosis and telomere shortening in A-T cells.Telomerase as a tumor-associated antigen for cancer immunotherapyGenomic organization of the Drosophila telomere retrotransposable elements.Telomere shortening occurs in subsets of normal breast epithelium as well as in situ and invasive carcinoma.Telomeres, stem cells, senescence, and cancer.Telomerase activation in cervical cancer.Defining the mode, energetics and specificity with which a macrocyclic hexaoxazole binds to human telomeric G-quadruplex DNAAdenovirus type 12 early region 1B 54K protein significantly extends the life span of normal mammalian cells in cultureCan ends justify the means?: telomeres and the mechanisms of replicative senescence and immortalization in mammalian cellsTelomerase activity, cell proliferation, and cancer.In situ analysis of changes in telomere size during replicative aging and cell transformation.Generation of mouse-human hybridomas secreting antibodies against peanut allergen Ara h1Immortalized cells as experimental models to study cancer.Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice.Telomerase activation in nasopharyngeal carcinomas.Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblastsTelomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferationReprogramming of telomerase by expression of mutant telomerase RNA template in human cells leads to altered telomeres that correlate with reduced cell viabilityDissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization.BRCA1/2 mutations perturb telomere biology: characterization of structural and functional abnormalities in vitro and in vivoA translocation-defective telomerase with low levels of activity and processivity stabilizes short telomeres and confers immortalization.Epitope analysis of peanut allergen Ara h1 with oligoclonal IgM antibody from human B-lymphoblastoid cells.Prospects and challenges of building a cancer vaccine targeting telomeraseBiosensor Techniques Used for Determination of Telomerase Activity in Cancer Cells.
P2860
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P2860
Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Stabilization of short telomer ...... ransformed human B lymphocytes
@ast
Stabilization of short telomer ...... ransformed human B lymphocytes
@en
type
label
Stabilization of short telomer ...... ransformed human B lymphocytes
@ast
Stabilization of short telomer ...... ransformed human B lymphocytes
@en
prefLabel
Stabilization of short telomer ...... ransformed human B lymphocytes
@ast
Stabilization of short telomer ...... ransformed human B lymphocytes
@en
P2093
P2860
P1433
P1476
Stabilization of short telomer ...... ransformed human B lymphocytes
@en
P2093
P2860
P304
P407
P577
1994-05-01T00:00:00Z