about
From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug designSARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulumStructure of the Main Protease from a Global Infectious Human Coronavirus, HCoV-HKU1Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV)Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit bindingA Brief Review: The Z-curve Theory and its Application in Genome Analysis.A rebuttal to the comments on the genome order index and the Z-curveMolecular epidemiology and evolutionary histories of human coronavirus OC43 and HKU1 among patients with upper respiratory tract infections in Kuala Lumpur, MalaysiaUnderstanding Human Coronavirus HCoV-NL63~!2009-11-13~!2010-04-09~!2010-05-25~!A Role for Neutrophils in Viral Respiratory Disease.The role of infections and coinfections with newly identified and emerging respiratory viruses in children.Interaction of severe acute respiratory syndrome-coronavirus and NL63 coronavirus spike proteins with angiotensin converting enzyme-2.Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesisViral and atypical bacterial detection in acute respiratory infection in children under five years.Detection of four human coronaviruses in respiratory infections in children: a one-year study in Colorado.Crystallization and preliminary crystallographic study of human coronavirus NL63 main protease in complex with an inhibitor.The coronavirus nucleocapsid is a multifunctional protein.Culturing the unculturable: human coronavirus HKU1 infects, replicates, and produces progeny virions in human ciliated airway epithelial cell cultures.Prevalence of antibodies to four human coronaviruses is lower in nasal secretions than in serumThe hydrophobic domain of infectious bronchitis virus E protein alters the host secretory pathway and is important for release of infectious virus.Human coronavirus NL63 utilizes heparan sulfate proteoglycans for attachment to target cellsCrystallization and preliminary crystallographic study of Porcine epidemic diarrhea virus main protease in complex with an inhibitorSynergistic inhibitor binding to the papain-like protease of human SARS coronavirus: mechanistic and inhibitor design implications.Development of human neutralizing monoclonal antibodies for prevention and therapy of MERS-CoV infectionsIdentification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screeningsInfection with human coronavirus NL63 enhances streptococcal adherence to epithelial cells.Identification of new respiratory viruses in the new millennium.Incorporation of spike and membrane glycoproteins into coronavirus virions.Human coronavirus OC43 3CL protease and the potential of ML188 as a broad-spectrum lead compound: homology modelling and molecular dynamic studies.A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins.Infection of human alveolar macrophages by human coronavirus strain 229E.HTCC: Broad Range Inhibitor of Coronavirus EntryCharacterization and complete genome sequence of human coronavirus NL63 isolated in ChinaRat coronaviruses infect rat alveolar type I epithelial cells and induce expression of CXC chemokines.Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium.Structure of Main Protease from Human Coronavirus NL63: Insights for Wide Spectrum Anti-Coronavirus Drug Design.The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies.Development of a nucleocapsid-based human coronavirus immunoassay and estimates of individuals exposed to coronavirus in a U.S. metropolitan population.Human coronavirus and severe acute respiratory infection in Southern Brazil.Host-pathogen interactions during coronavirus infection of primary alveolar epithelial cells.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The novel human coronaviruses NL63 and HKU1.
@ast
The novel human coronaviruses NL63 and HKU1.
@en
type
label
The novel human coronaviruses NL63 and HKU1.
@ast
The novel human coronaviruses NL63 and HKU1.
@en
prefLabel
The novel human coronaviruses NL63 and HKU1.
@ast
The novel human coronaviruses NL63 and HKU1.
@en
P2860
P50
P921
P356
P1433
P1476
The novel human coronaviruses NL63 and HKU1.
@en
P2860
P304
P356
10.1128/JVI.01466-06
P407
P577
2006-11-01T00:00:00Z