Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members.
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Functional analysis of H-Ryk, an atypical member of the receptor tyrosine kinase familyIsolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signalingHeregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3Association of csk-homologous kinase (CHK) (formerly MATK) with HER-2/ErbB-2 in breast cancer cellsActivation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferationAnalysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3Epidermal growth factor and betacellulin mediate signal transduction through co-expressed ErbB2 and ErbB3 receptorsTyrosine phosphorylation of selected secretory carrier membrane proteins, SCAMP1 and SCAMP3, and association with the EGF receptor.Interaction of the PA2G4 (EBP1) protein with ErbB-3 and regulation of this binding by heregulinPhosphotyrosine interactome of the ErbB-receptor kinase familyThe ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferationEssential function for ErbB3 in breast cancer proliferationHER-2 overexpression differentially alters transforming growth factor-beta responses in luminal versus mesenchymal human breast cancer cellsLapatinib Plasma and Tumor Concentrations and Effects on HER Receptor Phosphorylation in TumorCombining lapatinib (GW572016), a small molecule inhibitor of ErbB1 and ErbB2 tyrosine kinases, with therapeutic anti-ErbB2 antibodies enhances apoptosis of ErbB2-overexpressing breast cancer cells.The Under-Appreciated Promiscuity of the Epidermal Growth Factor Receptor FamilyExpression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylationHeregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptorTransformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2Interactions between progestins and heregulin (HRG) signaling pathways: HRG acts as mediator of progestins proliferative effects in mouse mammary adenocarcinomasARIA/HRG regulates AChR epsilon subunit gene expression at the neuromuscular synapse via activation of phosphatidylinositol 3-kinase and Ras/MAPK pathwayThe cellular response to neuregulins is governed by complex interactions of the erbB receptor familyDiversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactionsControlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimersNeuregulin-increased expression of acetylcholine receptor epsilon-subunit gene requires ErbB interaction with Shc.An incomplete program of cellular tyrosine phosphorylations induced by kinase-defective epidermal growth factor receptors.Biological and clinical significance of HER2 overexpression in breast cancer.The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma.Take your partners, please--signal diversification by the erbB family of receptor tyrosine kinases.ErbB tyrosine kinases and the two neuregulin families constitute a ligand-receptor network.In Vitro and In Vivo Anti-tumoral Effects of the Flavonoid Apigenin in Malignant Mesothelioma.Emerging therapies in gastrointestinal cancers.Role of receptor tyrosine kinases and their ligands in glioblastoma.Heregulin-stimulated acetylcholine receptor gene expression in muscle: requirement for MAP kinase and evidence for a parallel inhibitory pathway independent of electrical activity.ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling.Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancerThe C-terminus of the kinase-defective neuregulin receptor ErbB-3 confers mitogenic superiority and dictates endocytic routing.Ectopic expression of the ErbB-3 binding protein ebp1 inhibits growth and induces differentiation of human breast cancer cell lines.R-Ras3, a brain-specific Ras-related protein, activates Akt and promotes cell survival in PC12 cells.ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependency
P2860
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P2860
Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Efficient coupling with phosph ...... ther ErbB/EGFR family members.
@ast
Efficient coupling with phosph ...... ther ErbB/EGFR family members.
@en
type
label
Efficient coupling with phosph ...... ther ErbB/EGFR family members.
@ast
Efficient coupling with phosph ...... ther ErbB/EGFR family members.
@en
prefLabel
Efficient coupling with phosph ...... ther ErbB/EGFR family members.
@ast
Efficient coupling with phosph ...... ther ErbB/EGFR family members.
@en
P2093
P2860
P356
P1476
Efficient coupling with phosph ...... ther ErbB/EGFR family members.
@en
P2093
P2860
P304
P356
10.1128/MCB.14.1.492
P407
P577
1994-01-01T00:00:00Z