Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.
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OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamiliesRegulation of human hepatic drug transporter activity and expression by diesel exhaust particle extractInhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin.Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathyFunctional expression of the 11 human Organic Anion Transporting Polypeptides in insect cells reveals that sodium fluorescein is a general OATP substrate.Role of transmembrane domain 10 for the function of organic anion transporting polypeptide 1B1.Identification, Ki determination and CoMFA analysis of nuclear receptor ligands as competitive inhibitors of OATP1B1-mediated estradiol-17beta-glucuronide transportXenobiotic, bile acid, and cholesterol transporters: function and regulation.The Importance of Steroid Uptake and Intracrine Action in Endometrial and Ovarian Cancers.Organic anion transporting polypeptide 1B3 can form homo- and hetero-oligomersDevelopment of a cell-based high-throughput assay to screen for inhibitors of organic anion transporting polypeptides 1B1 and 1B3.Mechanism of polybrominated diphenyl ether uptake into the liver: PBDE congeners are substrates of human hepatic OATP transportersFluorescence-based assays for the assessment of drug interaction with the human transporters OATP1B1 and OATP1B3Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1.The SLCO (former SLC21) superfamily of transporters.Several conserved positively charged amino acids in OATP1B1 are involved in binding or translocation of different substratesImpact of OATP transporters on pharmacokinetics.Molecular cloning and functional characterization of a rainbow trout liver Oatp.Interactions of green tea catechins with organic anion-transporting polypeptides.Proteasome regulator marizomib (NPI-0052) exhibits prolonged inhibition, attenuated efflux, and greater cytotoxicity than its reversible analogsIsolation of modulators of the liver-specific organic anion-transporting polypeptides (OATPs) 1B1 and 1B3 from Rollinia emarginata Schlecht (Annonaceae).Functional characterization of liver enhancers that regulate drug-associated transporters.The expression and function of organic anion transporting polypeptides in normal tissues and in cancerWhole-genome studies identify solute carrier transporters in cellular susceptibility to paclitaxel.Influence of polymorphic OATP1B-type carriers on the disposition of docetaxel.Organic anion transporting polypeptides OATP1B1 and OATP1B3 and their genetic variants influence the pharmacokinetics and pharmacodynamics of raloxifeneTransport by OATP1B1 and OATP1B3 enhances the cytotoxicity of epigallocatechin 3-O-gallate and several quercetin derivatives.Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1Functional identification of a novel transport system for endogenous and synthetic opioid peptides in the rabbit conjunctival epithelial cell line CJVE.Amino acid residues in transmembrane domain 10 of organic anion transporting polypeptide 1B3 are critical for cholecystokinin octapeptide transport.Downregulation of Organic Anion Transporting Polypeptide (OATP) 1B1 Transport Function by Lysosomotropic Drug Chloroquine: Implication in OATP-Mediated Drug-Drug InteractionsDrug interactions at the blood-brain barrier: fact or fantasy?Organic anion-transporting polypeptides.Hypervascular hepatocellular carcinoma: correlation between biologic features and signal intensity on gadoxetic acid-enhanced MR imagesPharmacogenetics of drug-induced liver injury.Genetic variations of bile salt transporters as predisposing factors for drug-induced cholestasis, intrahepatic cholestasis of pregnancy and therapeutic response of viral hepatitis.Nuclear-receptor-mediated regulation of drug- and bile-acid-transporter proteins in gut and liver.Primary hepatocyte cultures as prominent in vitro tools to study hepatic drug transporters.Transporter-mediated drug-drug interactions with oral antidiabetic drugs.Hepatic metabolism and disposition of baicalein via the coupling of conjugation enzymes and transporters-in vitro and in vivo evidences.
P2860
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P2860
Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.
@ast
Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.
@en
type
label
Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.
@ast
Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.
@en
prefLabel
Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.
@ast
Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.
@en
P2093
P2860
P1476
Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.
@en
P2093
Bret Wahlgren
Bruno Hagenbuch
Bruno Stieger
Chunshan Gui
Lucas Thompson
Melissa Mock
P2860
P356
10.1016/J.EJPHAR.2008.01.042
P407
P577
2008-02-08T00:00:00Z