Filamentous actin regulates insulin exocytosis through direct interaction with Syntaxin 4.
about
Syntaxin-4 defines a domain for activity-dependent exocytosis in dendritic spinesMultiple roles for the actin cytoskeleton during regulated exocytosisSignaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cellsA novel role for the centrosomal protein, pericentrin, in regulation of insulin secretory vesicle docking in mouse pancreatic beta-cellsCytoskeletal dependence of insulin granule movement dynamics in INS-1 beta-cells in response to glucoseOrganization and dynamics of SNARE proteins in the presynaptic membraneGlucose deprivation regulates KATP channel trafficking via AMP-activated protein kinase in pancreatic beta-cellsInsulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cellsIdentification of a distal GLUT4 trafficking event controlled by actin polymerizationCholesterol regulates glucose-stimulated insulin secretion through phosphatidylinositol 4,5-bisphosphate.Glucose-induced ERM protein activation and translocation regulates insulin secretionA proteomic study of cMyc improvement of CHO culture.Nephrin is expressed on the surface of insulin vesicles and facilitates glucose-stimulated insulin release.Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4Phospholipase C-related catalytically inactive protein (PRIP) controls KIF5B-mediated insulin secretionDisruption of the actin cytoskeleton induces fluorescent glucose accumulation on the rat hepatocytes Clone 9.A network of networks: cytoskeletal control of compartmentalized function within dendritic spines.Gene networks modified by sulphonylureas in beta cells: a pathway-based analysis of insulin secretion and cell death.High glucose predisposes gene expression and ERK phosphorylation to apoptosis and impaired glucose-stimulated insulin secretion via the cytoskeletonInsulin secretion induced by glucose-dependent insulinotropic polypeptide requires phosphatidylinositol 3-kinase γ in rodent and human β-cells.Phosphatidylinositol-4-phosphate-5-kinase alpha deficiency alters dynamics of glucose-stimulated insulin release to improve glucohomeostasis and decrease obesity in mice.Focal adhesion remodeling is crucial for glucose-stimulated insulin secretion and involves activation of focal adhesion kinase and paxillin.Mechanisms and function of dendritic exocytosis.Stimulus-induced S-nitrosylation of Syntaxin 4 impacts insulin granule exocytosisBAG3 regulates formation of the SNARE complex and insulin secretionDoc2b serves as a scaffolding platform for concurrent binding of multiple Munc18 isoforms in pancreatic islet β-cellsGelsolin associates with the N terminus of syntaxin 4 to regulate insulin granule exocytosis.Novel mechanistic link between focal adhesion remodeling and glucose-stimulated insulin secretionDynamical Organization of Syntaxin-1A at the Presynaptic Active ZoneIn vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule traffickingMunc18-1 regulates first-phase insulin release by promoting granule docking to multiple syntaxin isoformsThe good and bad effects of cysteine S-nitrosylation and tyrosine nitration upon insulin exocytosis: a balancing act.Secretagogin affects insulin secretion in pancreatic β-cells by regulating actin dynamics and focal adhesionIdentification and Characterization of a Candidate Wolbachia pipientis Type IV Effector That Interacts with the Actin Cytoskeleton.Novel aspects of the molecular mechanisms controlling insulin secretion.Ezrin mediates tethering of the gamma-aminobutyric acid transporter GAT1 to actin filaments via a C-terminal PDZ-interacting domain.CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release.Leptin regulates KATP channel trafficking in pancreatic β-cells by a signaling mechanism involving AMP-activated protein kinase (AMPK) and cAMP-dependent protein kinase (PKA).Cab45b, a Munc18b-interacting partner, regulates exocytosis in pancreatic beta-cells.Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins.
P2860
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P2860
Filamentous actin regulates insulin exocytosis through direct interaction with Syntaxin 4.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Filamentous actin regulates in ...... t interaction with Syntaxin 4.
@ast
Filamentous actin regulates in ...... t interaction with Syntaxin 4.
@en
type
label
Filamentous actin regulates in ...... t interaction with Syntaxin 4.
@ast
Filamentous actin regulates in ...... t interaction with Syntaxin 4.
@en
prefLabel
Filamentous actin regulates in ...... t interaction with Syntaxin 4.
@ast
Filamentous actin regulates in ...... t interaction with Syntaxin 4.
@en
P2093
P2860
P356
P1476
Filamentous actin regulates in ...... t interaction with Syntaxin 4.
@en
P2093
Debbie C Thurmond
Jenna L Jewell
Zhanxiang Wang
P2860
P304
10716-10726
P356
10.1074/JBC.M709876200
P407
P577
2008-02-19T00:00:00Z