The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr.
about
RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cellsA naturally occurring soluble isoform of murine Fas generated by alternative splicingTh1 CD4+ lymphocytes delete activated macrophages through the Fas/APO-1 antigen pathway.The apoptosis-1/Fas protein in human systemic lupus erythematosus.Increased expression of the pro-apoptotic protein BIM, a mechanism for cAMP/protein kinase A (PKA)-induced apoptosis of immature T cells.CD95 (Fas) may control the expansion of activated T cells after elimination of bacteria in murine listeriosis.Renal glycosphingolipid metabolism is dysfunctional in lupus nephritis.Fas antigen expression and its relationship with apoptosis in human hepatocellular carcinoma and noncancerous tissues.TWEAK/Fn14 Signaling Involvement in the Pathogenesis of Cutaneous Disease in the MRL/lpr Model of Spontaneous Lupus.Peripheral deletion of rheumatoid factor B cells after abortive activation by IgG.Polymorphism of murine Fas ligand that affects the biological activityRadiation and stress-induced apoptosis: a role for Fas/Fas ligand interactions.The role of B cells in lpr/lpr-induced autoimmunity.Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus.T cells with gamma/delta T cell receptors (TCR) of intestinal type are preferentially expanded in TCR-alpha-deficient lpr mice.CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway.Mutation in fas ligand impairs maturation of thymocytes bearing moderate affinity T cell receptorsAn essential role for c-FLIP in the efficient development of mature T lymphocytes.Recent advances and opportunities in research on lupus: environmental influences and mechanisms of disease.Infectivity and insertional mutagenesis of endogenous retrovirus in autoimmune NZB and B/W mice.Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas.Mesenchymal stem cell transplantation reverses multiorgan dysfunction in systemic lupus erythematosus mice and humans.Tolerance induction ameliorates allograft vasculopathy in rat aortic transplants. Influence of Fas-mediated apoptosis.Biphasic onset of splenic apoptosis following hemorrhagic shock: critical implications for Bax, Bcl-2, and Mcl-1 proteins.A novel signaling mechanism for soluble CD95 ligand. Synergy with anti-CD95 monoclonal antibodies for apoptosis and NF-kappaB nuclear translocation.Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment.Thymocyte development in the absence of matrix metalloproteinase-9/gelatinase B.Inhibition of tumor necrosis factor alpha by an adenovirus-encoded soluble fusion protein extends transgene expression in the liver and lung.T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions.Cell-mediated cytotoxicity in perforin-less mice.Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders.A physical interaction between the cell death protein Fas and the tyrosine kinase p59fynT.Cellular interactions in the lpr and gld models of systemic autoimmunity.Massive upregulation of the Fas ligand in lpr and gld mice: implications for Fas regulation and the graft-versus-host disease-like wasting syndrome.Fas receptor (CD95)-mediated apoptosis in leukemic cells.The role of antibodies to DNA in systemic lupus erythematosus--a review and introduction to an international workshop on DNA antibodies held in London, May 1996.A role for the Fas antigen in lupus?Cytotoxicity of fresh NK1.1+ T cell receptor alpha/beta+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target.Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody.Fas-mediated cytotoxicity by freshly isolated natural killer cells.
P2860
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P2860
The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
The Fas protein is expressed a ...... pus-prone strain, MRL lpr/lpr.
@ast
The Fas protein is expressed a ...... pus-prone strain, MRL lpr/lpr.
@en
type
label
The Fas protein is expressed a ...... pus-prone strain, MRL lpr/lpr.
@ast
The Fas protein is expressed a ...... pus-prone strain, MRL lpr/lpr.
@en
prefLabel
The Fas protein is expressed a ...... pus-prone strain, MRL lpr/lpr.
@ast
The Fas protein is expressed a ...... pus-prone strain, MRL lpr/lpr.
@en
P2093
P2860
P356
P1476
The Fas protein is expressed a ...... pus-prone strain, MRL lpr/lpr.
@en
P2093
P2860
P304
10340-10344
P356
10.1073/PNAS.90.21.10340
P407
P577
1993-11-01T00:00:00Z