Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.

Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.

Item
http://www.wikidata.org/entity/Q36654350
ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaksAID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.Origin of chromosomal translocations in lymphoid cancer.Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes.ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification.The RAG2 C terminus suppresses genomic instability and lymphomagenesis.Rapid analysis of chromosome aberrations in mouse B lymphocytes by PNA-FISH.Kinase-dead ATM protein causes genomic instability and early embryonic lethality in miceConcurrent V(D)J recombination and DNA end instability increase interchromosomal trans-rearrangements in ATM-deficient thymocytesThe RAG2 C-terminus and ATM protect genome integrity by controlling antigen receptor gene cleavage.How does DNA break during chromosomal translocations?A new take on v(d)j recombination: transcription driven nuclear and chromatin reorganization in rag-mediated cleavage.It takes two: communication between homologous alleles preserves genomic stability during V(D)J recombination.Tcrδ translocations that delete the Bcl11b haploinsufficient tumor suppressor gene promote atm-deficient T cell acute lymphoblastic leukemia.Somatic inactivation of ATM in hematopoietic cells predisposes mice to cyclin D3 dependent T cell acute lymphoblastic leukemia.
P2860

Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.

Item
http://www.wikidata.org/entity/Q36654350
description
2009 nî lūn-bûn
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2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.
@ast
Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.
@en
type
label
Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.
@ast
Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.
@en
prefLabel
Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.
@ast
Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932