Nuclear punctate distribution of ALL-1 is conferred by distinct elements at the N terminus of the protein
about
Self-association of the SET domains of human ALL-1 and of Drosophila TRITHORAX and ASH1 proteinshuASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctionsNovel alternative splicing and nuclear localization of human RGS12 gene productsProtein interactions of the MLL PHD fingers modulate MLL target gene regulation in human cells.Hepatitis B virus pX interacts with HBXAP, a PHD finger protein to coactivate transcriptionNew insight into the molecular mechanisms of MLL-associated leukemiaProteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localizationThe elongation domain of ELL is dispensable but its ELL-associated factor 1 interaction domain is essential for MLL-ELL-induced leukemogenesisMLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding proteinMolecular Mechanism of MLL PHD3 and RNA Recognition by the Cyp33 RRM DomainThe autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding proteinThe ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3Modulation of cell cycle by graded expression of MLL-AF4 fusion oncoproteinFunctional contribution of EEN to leukemogenic transformation by MLL-EEN fusion proteinCpG-binding protein is a nuclear matrix- and euchromatin-associated protein localized to nuclear speckles containing human trithorax. Identification of nuclear matrix targeting signalsENL, the MLL fusion partner in t(11;19), binds to the c-Abl interactor protein 1 (ABI1) that is fused to MLL in t(10;11)+.Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibitionMll rearrangements in haematological malignancies: lessons from clinical and biological studies.Developmentally induced Mll1 loss reveals defects in postnatal haematopoiesisMolecular mechanisms of leukemogenesis mediated by MLL fusion proteins.Mutant alleles of the Drosophila trithorax gene produce common and unusual homeotic and other developmental phenotypes.Autoimmune regulator: from loss of function to autoimmunity.The amino terminus of the mixed lineage leukemia protein (MLL) promotes cell cycle arrest and monocytic differentiationMLL 5 protein forms intranuclear foci, and overexpression inhibits cell cycle progressionThe biological and clinical significance of MLL abnormalities in haematological malignancies.Acute leukemia in early childhood.Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein.MLL-Rearranged Leukemias-An Update on Science and Clinical Approaches.MLL-SEPTIN gene fusions in hematological malignancies.Septin roles in tumorigenesis.In focus: MLL-rearranged leukemia.MLL-ENL cooperates with SCF to transform primary avian multipotent cells.Gamma interferon-dependent transcriptional memory via relocalization of a gene locus to PML nuclear bodies.Multiple mixed lineage leukemia (MLL) fusion proteins suppress p53-mediated response to DNA damage.Truncation of the Mll gene in exon 5 by gene targeting leads to early preimplantation lethality of homozygous embryos.Molecular and cellular issues of KMT2A variants involved in Wiedemann-Steiner syndrome.Expression of leukemic MLL fusion proteins in Drosophila affects cell cycle control and chromosome morphology.MLL-mediated transcriptional gene regulation investigated by gene expression profiling.
P2860
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P2860
Nuclear punctate distribution of ALL-1 is conferred by distinct elements at the N terminus of the protein
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Nuclear punctate distribution ...... the N terminus of the protein
@ast
Nuclear punctate distribution ...... the N terminus of the protein
@en
type
label
Nuclear punctate distribution ...... the N terminus of the protein
@ast
Nuclear punctate distribution ...... the N terminus of the protein
@en
prefLabel
Nuclear punctate distribution ...... the N terminus of the protein
@ast
Nuclear punctate distribution ...... the N terminus of the protein
@en
P2093
P2860
P356
P1476
Nuclear punctate distribution ...... the N terminus of the protein
@en
P2093
J Blechman
T Nakamura
P2860
P304
P356
10.1073/PNAS.94.14.7286
P407
P577
1997-07-01T00:00:00Z