Altered Hox expression and segmental identity in Mll-mutant mice
about
The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3Dual function of histone H3 lysine 36 methyltransferase ASH1 in regulation of Hox gene expressionGenome-wide survey and developmental expression mapping of zebrafish SET domain-containing genesMSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25)AF15q14, a novel partner gene fused to the MLL gene in an acute myeloid leukaemia with a t(11;15)(q23;q14)The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complexLeukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expressionWdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genesHistone methyltransferase MLL1 regulates MDR1 transcription and chemoresistanceSolution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferaseThe t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repressionThe PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesisMolecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASSAssociation of SET domain and myotubularin-related proteins modulates growth controlNew insight into the molecular mechanisms of MLL-associated leukemiaInteraction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cellsOn the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complexInteraction of mouse polycomb-group (Pc-G) proteins Enx1 and Enx2 with Eed: indication for separate Pc-G complexes.Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeresThe MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expressionMLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein functionThe leucine zipper motif of the Drosophila AF10 homologue can inhibit PRE-mediated repression: implications for leukemogenic activity of human MLL-AF10 fusionsProteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localizationMLL and CREB bind cooperatively to the nuclear coactivator CREB-binding proteinLeukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteinsCREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicityEEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemiaInvolvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemiaHoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalizationHistone methylation regulates memory formation.Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 geneRegulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalizationRecombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of themMLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding proteinMammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genesNovel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partnerThe many faces of histone H3K79 methylationRevisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemiaHistone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and prevention
P2860
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P2860
Altered Hox expression and segmental identity in Mll-mutant mice
description
1995 nî lūn-bûn
@nan
1995 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Altered Hox expression and segmental identity in Mll-mutant mice
@ast
Altered Hox expression and segmental identity in Mll-mutant mice
@en
type
label
Altered Hox expression and segmental identity in Mll-mutant mice
@ast
Altered Hox expression and segmental identity in Mll-mutant mice
@en
prefLabel
Altered Hox expression and segmental identity in Mll-mutant mice
@ast
Altered Hox expression and segmental identity in Mll-mutant mice
@en
P2093
P3181
P356
P1433
P1476
Altered Hox expression and segmental identity in Mll-mutant mice
@en
P2093
P2888
P3181
P356
10.1038/378505A0
P407
P577
1995-11-30T00:00:00Z
P6179
1034280981