Age-appropriate cognition and subtle dopamine-independent motor deficits in aged tau knockout mice
about
Tau: The Center of a Signaling Nexus in Alzheimer's DiseaseTau missorting and spastin-induced microtubule disruption in neurodegeneration: Alzheimer Disease and Hereditary Spastic ParaplegiaAntisense oligonucleotides: treating neurodegeneration at the level of RNATau physiology and pathomechanisms in frontotemporal lobar degenerationTau Biology and Tau-Directed Therapies for Alzheimer's DiseaseAlpha-synuclein and tau: teammates in neurodegeneration?Ketogenic diet improves motor performance but not cognition in two mouse models of Alzheimer's pathologySeizure resistance without parkinsonism in aged mice after tau reductionLoss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with agingMotor and cognitive deficits in aged tau knockout mice in two background strains.Tau reduction diminishes spatial learning and memory deficits after mild repetitive traumatic brain injury in mice.Tau reduction prevents disease in a mouse model of Dravet syndromeTau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3β.Humanized Tau Mice with Regionalized Amyloid Exhibit Behavioral Deficits but No Pathological Interaction.No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin MiceAbsence of Tau triggers age-dependent sciatic nerve morphofunctional deficits and motor impairmentExpression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice.What Renders TAU ToxicImpaired burrowing is the most prominent behavioral deficit of aging htau mice.Antisense reduction of tau in adult mice protects against seizuresClinical trials: past, current, and future for atypical Parkinsonian syndromes.Invited review: Drug development for tauopathies.Tau deletion promotes brain insulin resistanceTau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.Therapeutic Strategies for Restoring Tau Homeostasis.Tau and spectraplakins promote synapse formation and maintenance through Jun kinase and neuronal trafficking.Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening.Neuroepigenetic mechanisms in disease.Emerging Diagnostic and Therapeutic Strategies for Tauopathies.Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice.Atypical, non-standard functions of the microtubule associated Tau protein.Importance of tau in cognitive decline as revealed by developmental exposure to lead.Antisense oligonucleotides: the next frontier for treatment of neurological disorders.Tau Deficiency Down-Regulated Transcription Factor Orthodenticle Homeobox 2 Expression in the Dopaminergic Neurons in Ventral Tegmental Area and Caused No Obvious Motor Deficits in Mice.A role for tau in learning, memory and synaptic plasticity.Tau Deletion Prevents Stress-Induced Dendritic Atrophy in Prefrontal Cortex: Role of Synaptic Mitochondria.
P2860
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P2860
Age-appropriate cognition and subtle dopamine-independent motor deficits in aged tau knockout mice
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Age-appropriate cognition and ...... cits in aged tau knockout mice
@ast
Age-appropriate cognition and ...... cits in aged tau knockout mice
@en
type
label
Age-appropriate cognition and ...... cits in aged tau knockout mice
@ast
Age-appropriate cognition and ...... cits in aged tau knockout mice
@en
prefLabel
Age-appropriate cognition and ...... cits in aged tau knockout mice
@ast
Age-appropriate cognition and ...... cits in aged tau knockout mice
@en
P2093
P2860
P1476
Age-appropriate cognition and ...... cits in aged tau knockout mice
@en
P2093
Anthony Adame
Lennart Mucke
Meaghan Morris
Nino Devidze
Patricia Hamto
P2860
P304
P356
10.1016/J.NEUROBIOLAGING.2012.12.003
P577
2013-01-16T00:00:00Z