The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor.
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GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunitBcr-Abl oncoproteins bind directly to activators of the Ras signalling pathwayPhosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivoInteraction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: structural features and analysis of conformational changesSHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain.Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferationp21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating proteinAssociation of hematopoietic cell phosphatase with c-Kit after stimulation with c-Kit ligandDirect association of p110 beta phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110 betaKit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferationIntracellular signaling mechanisms leading to synergistic effects of endothelin-1 and stem cell factor on proliferation of cultured human melanocytes. Cross-talk via trans-activation of the tyrosine kinase c-kit receptorDown-regulation of LFA-1-mediated T cell adhesion induced by the HIV envelope glycoprotein gp160 requires phosphatidylinositol-3-kinase activityThe MATK tyrosine kinase interacts in a specific and SH2-dependent manner with c-KitSteel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL)Tyrosine phosphorylation of the related adhesion focal tyrosine kinase in megakaryocytes upon stem cell factor and phorbol myristate acetate stimulation and its association with paxillinThe complexity of KIT gene mutations and chromosome rearrangements and their clinical correlation in gastrointestinal stromal (pacemaker cell) tumorsSTAT protein recruitment and activation in c-Kit deletion mutantsInvolvement of phospholipase Cgamma1 in mouse egg activation induced by a truncated form of the C-kit tyrosine kinase present in spermatozoa.The v-Src SH3 domain binds phosphatidylinositol 3'-kinase.c-Kit-kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor and stimulates mitogen-activated protein kinase but is down-regulated in melanomas.Gastrointestinal stromal tumor and its targeted therapeutics.Physiology and pathophysiology of the interstitial cells of Cajal: from bench to bedside. IV. Genetic and animal models of GI motility disorders caused by loss of interstitial cells of Cajal.Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responsesMolecular mechanisms utilized by alternative c-kit gene products in the control of spermatogonial proliferation and sperm-mediated egg activation.Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptorsMolecular genetics and the ontogeny of pigment patterns in mammals.The c-kit proto-oncogene in normal and malignant human hematopoiesis.Targeting mutated tyrosine kinases in the therapy of myeloid leukaemias.Reversible expansion of primate mast cell populations in vivo by stem cell factor.The c-kit ligand, stem cell factor, promotes mast cell survival by suppressing apoptosis.Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinaseExpression of functional c-kit receptors rescues the genetic defect of W mutant mast cellsUpdate on the biology and therapy of gastrointestinal stromal tumors.Cytokine-mediated protein kinase C activation is a signal for lineage determination in bipotential granulocyte macrophage colony-forming cells.Hepatocyte growth factor induces proliferation and differentiation of multipotent and erythroid hemopoietic progenitors.Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice.Stem cell factor expression, mast cells and inflammation in asthma.Nf1 regulates hematopoietic progenitor cell growth and ras signaling in response to multiple cytokines.Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase.Mitogenic signalling and substrate specificity of the Flk2/Flt3 receptor tyrosine kinase in fibroblasts and interleukin 3-dependent hematopoietic cells
P2860
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P2860
The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
The Steel/W transduction pathw ...... s induced by the Steel factor.
@ast
The Steel/W transduction pathw ...... s induced by the Steel factor.
@en
type
label
The Steel/W transduction pathw ...... s induced by the Steel factor.
@ast
The Steel/W transduction pathw ...... s induced by the Steel factor.
@en
prefLabel
The Steel/W transduction pathw ...... s induced by the Steel factor.
@ast
The Steel/W transduction pathw ...... s induced by the Steel factor.
@en
P2093
P2860
P356
P1476
The Steel/W transduction pathw ...... is induced by the Steel factor
@en
P2093
A Bernstein
D E Williams
D M Anderson
P2860
P304
P356
10.1128/MCB.11.6.3043
P407
P577
1991-06-01T00:00:00Z