Immunization with live attenuated simian immunodeficiency virus induces strong type 1 T helper responses and beta-chemokine production
about
Characterization of CD8+ T cell differentiation following SIVΔnef vaccination by transcription factor expression profilingADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challengeLower levels of gamma interferon expressed by a pseudotyped single-cycle simian immunodeficiency virus enhance immunogenicity in rats.Inhibitory TCR coreceptor PD-1 is a sensitive indicator of low-level replication of SIV and HIV-1Suppression of acute viremia by short-term postexposure prophylaxis of simian/human immunodeficiency virus SHIV-RT-infected monkeys with a novel reverse transcriptase inhibitor (GW420867) allows for development of potent antiviral immune responses rImmunization of macaques with single-cycle simian immunodeficiency virus (SIV) stimulates diverse virus-specific immune responses and reduces viral loads after challenge with SIVmac239Novel, live attenuated simian immunodeficiency virus constructs containing major deletions in leader RNA sequencesUsing death to one's advantage: HIV modulation of apoptosis.High beta-chemokine expression levels in lymphoid tissues of simian/human immunodeficiency virus 89.6-vaccinated rhesus macaques are associated with uncontrolled replication of simian immunodeficiency virus challenge inoculum.Rev-independent simian immunodeficiency virus strains are nonpathogenic in neonatal macaques.Live, attenuated simian immunodeficiency virus SIVmac-M4, with point mutations in the Env transmembrane protein intracytoplasmic domain, provides partial protection from mucosal challenge with pathogenic SIVmac251.Mucosal priming of simian immunodeficiency virus-specific cytotoxic T-lymphocyte responses in rhesus macaques by the Salmonella type III secretion antigen delivery system.Induction of a virus-specific effector-memory CD4+ T cell response by attenuated SIV infection.Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.Vaccination of rhesus macaques with a vif-deleted simian immunodeficiency virus proviral DNA vaccine.Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus.Macaques vaccinated with live-attenuated SIV control replication of heterologous virus.Diverse recognition of conserved orthopoxvirus CD8+ T cell epitopes in vaccinated rhesus macaques.Flow cytometry based identification of simian immunodeficiency virus Env-specific B lymphocytes.The simian immunodeficiency virus deltaNef vaccine, after application to the tonsils of Rhesus macaques, replicates primarily within CD4(+) T cells and elicits a local perforin-positive CD8(+) T-cell response.Vaccination with SIVmac239Deltanef activates CD4+ T cells in the absence of CD4 T-cell loss.Identification of broadly recognized, T helper 1 lymphocyte epitopes in an equine lentivirus.Modulation of immunity and viral-host interactions by alcohol.Expression of CD8alpha identifies a distinct subset of effector memory CD4+ T lymphocytes.Immunogenicity of a DNA prime and recombinant adenovirus boost regime significantly varies between rhesus macaques of Chinese and Indian origins.
P2860
Q27320870-6893F49C-B0C0-40ED-BCD2-5340278AED9BQ27342615-CCC05D53-CA8B-491A-BFCE-3BB4B4F8B6D2Q30373857-9F17FE0C-A524-40E0-8F54-D6ADB9362162Q33606773-84565380-BCA8-4C36-ABA3-AE6BD0B919A4Q33806166-3F9C1683-FA0D-4F40-AF4D-8747CC18C904Q33843131-84339EC1-C0DB-4327-BE1C-8EB22AA613FDQ33865700-AE5A4051-29B8-4FC5-BB0B-C5F1B6B7D702Q34173884-6637ED67-9229-40E1-B7C6-410644959D70Q34192490-19D8FDF0-BA12-4976-8EB4-6593FA252A4CQ34327256-CB3A96DC-7CB6-4974-82C9-07B15E892448Q34354961-E701B9A5-8DFC-46EF-A15D-4F954EB07904Q34471356-BE57E359-A30E-47EF-9F17-BBAD5B2EDABBQ36228123-499E1238-C62A-4711-9248-AF18BD2B14EFQ36524357-A886523E-35B1-4B86-957C-E1723FCED83DQ36846517-7055702F-51D6-4FBC-975C-3B997CE93B95Q36853450-FE0B7775-75E4-44BB-9349-173D48F2B798Q36946545-714CFD00-5D83-43DB-B216-9E14DE25F1EBQ37395140-F50C1A51-B424-41E9-95B1-120D2210FF06Q39521335-1DD5BFE4-3BD4-4824-8A12-FEA0268AB53FQ39686091-C2AC426B-277F-41F2-A683-B51260DAF6A3Q41816425-81397E67-D9EE-44C3-8010-215455A30154Q43522584-5DC1DBF5-9510-41BF-B317-EE9DA013302DQ44261125-4C274B99-3C5C-4D33-8198-F9ACF5B8CADEQ51981076-33E4BBDF-364E-49AC-8616-126EAD69FE6FQ53565788-E2CC7977-03C2-4EDD-8ADE-14D29828A990
P2860
Immunization with live attenuated simian immunodeficiency virus induces strong type 1 T helper responses and beta-chemokine production
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Immunization with live attenua ...... and beta-chemokine production
@ast
Immunization with live attenua ...... and beta-chemokine production
@en
type
label
Immunization with live attenua ...... and beta-chemokine production
@ast
Immunization with live attenua ...... and beta-chemokine production
@en
prefLabel
Immunization with live attenua ...... and beta-chemokine production
@ast
Immunization with live attenua ...... and beta-chemokine production
@en
P2093
P2860
P921
P356
P1476
Immunization with live attenua ...... and beta-chemokine production
@en
P2093
P2860
P304
14031-14036
P356
10.1073/PNAS.96.24.14031
P407
P577
1999-11-01T00:00:00Z