FANCJ couples replication past natural fork barriers with maintenance of chromatin structure.
about
Getting Ready for the Dance: FANCJ Irons Out DNA WrinklesInterplay between Fanconi anemia and homologous recombination pathways in genome integrityG-quadruplexes and helicasesLinking replication stress with heterochromatin formationInhibition of Topoisomerase (DNA) I (TOP1): DNA Damage Repair and Anticancer TherapyReplication of Structured DNA and its implication in epigenetic stabilityReplication fork instability and the consequences of fork collisions from rereplicationInsight into the roles of helicase motif Ia by characterizing Fanconi anemia group J protein (FANCJ) patient mutationsNovel function of the Fanconi anemia group J or RECQ1 helicase to disrupt protein-DNA complexes in a replication protein A-stimulated manner.Repair of O6-methylguanine adducts in human telomeric G-quadruplex DNA by O6-alkylguanine-DNA alkyltransferase.Association of G-quadruplex forming sequences with human mtDNA deletion breakpoints.Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemiaA distinct triplex DNA unwinding activity of ChlR1 helicaseDNA-damage foci to detect and characterize DNA repair alterations in children treated for pediatric malignanciesG-quadruplexes significantly stimulate Pif1 helicase-catalyzed duplex DNA unwinding.RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ.DNA helicases involved in DNA repair and their roles in cancerFANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex.FANCJ suppresses microsatellite instability and lymphomagenesis independent of the Fanconi anemia pathway.FANCJ at the FORK.DNA structure matters.Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability.FANCJ is essential to maintain microsatellite structure genome-wide during replication stress.G-quadruplex recognition and remodeling by the FANCJ helicaseG-quadruplex interacting small molecules and drugs: from bench toward bedside.FANCJ protein is important for the stability of FANCD2/FANCI proteins and protects them from proteasome and caspase-3 dependent degradation.Distinct cellular phenotype linked to defective DNA interstrand crosslink repair and homologous recombinationNucleotide Pool Depletion Induces G-Quadruplex-Dependent Perturbation of Gene Expression.Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress.Determinants of G quadruplex-induced epigenetic instability in REV1-deficient cells.Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responsesReplication stalling and DNA microsatellite instability.The BRCA1 Ubiquitin ligase function sets a new trend for remodelling in DNA repair.Forks on the Run: Can the Stalling of DNA Replication Promote Epigenetic Changes?FANCJ helicase controls the balance between short- and long-tract gene conversions between sister chromatids.Quadruplex-forming DNA sequences spread by retrotransposons may serve as genome regulators.FANCJ promotes DNA synthesis through G-quadruplex structures.A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites.RecQ and Fe-S helicases have unique roles in DNA metabolism dictated by their unwinding directionality, substrate specificity, and protein interactions.
P2860
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P2860
FANCJ couples replication past natural fork barriers with maintenance of chromatin structure.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
FANCJ couples replication past ...... enance of chromatin structure.
@ast
FANCJ couples replication past ...... enance of chromatin structure.
@en
type
label
FANCJ couples replication past ...... enance of chromatin structure.
@ast
FANCJ couples replication past ...... enance of chromatin structure.
@en
prefLabel
FANCJ couples replication past ...... enance of chromatin structure.
@ast
FANCJ couples replication past ...... enance of chromatin structure.
@en
P2860
P356
P1476
FANCJ couples replication past ...... enance of chromatin structure.
@en
P2093
Jadwiga Nieminuszczy
Rebekka A Schwab
P2860
P356
10.1083/JCB.201208009
P407
P577
2013-03-25T00:00:00Z