about
Roles for retrotransposon insertions in human diseaseSTING: infection, inflammation and cancerReplication and transcription on a collision course: eukaryotic regulation mechanisms and implications for DNA stabilityDNA sensor cGAS-mediated immune recognitionCharacterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging AlphavirusesNonspecific DNA Binding of cGAS N Terminus Promotes cGAS Activation.Friend or Foe: Innate Sensing of HIV in the Female Reproductive Tract.Aicardi-Goutières syndrome and the type I interferonopathies.DNA polymerase-α regulates the activation of type I interferons through cytosolic RNA:DNA synthesisGenome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome.cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells.Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous RetrovirusesA new model to study neurodegeneration in ataxia oculomotor apraxia type 2Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNACytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGASRNase H2 catalytic core Aicardi-Goutières syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice.Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.Intracellular detection of viral nucleic acids.The Emerging Roles of STING in Bacterial Infections.PRRs are watching you: Localization of innate sensing and signaling regulators.The cGAS-STING Defense Pathway and Its Counteraction by Viruses.Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses.Activation of cGAS-dependent antiviral responses by DNA intercalating agents.Viral evasion of DNA-stimulated innate immune responses.Suppression of Type I Interferon Production by Human T-Cell Leukemia Virus Type 1 Oncoprotein Tax through Inhibition of IRF3 Phosphorylation.Discriminating self from non-self in nucleic acid sensing.cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling.Crosstalk between Cytoplasmic RIG-I and STING Sensing Pathways.Cytosolic nucleic acid sensors and innate immune regulation.The Impact of the Interferon/TNF-Related Apoptosis-Inducing Ligand Signaling Axis on Disease Progression in Respiratory Viral Infection and Beyond.Mitochondrial DNA in innate immune responses and inflammatory pathology.Collateral Damage during Dengue Virus Infection: Making Sense of DNA by cGAS.Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen: Replicating and Shielding Viral DNA during Viral Persistence.Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition.Tumour viruses and innate immunity.Ku70 Senses HTLV-1 DNA and Modulates HTLV-1 Replication.cGAMP Quantification in Virus-Infected Human Monocyte-Derived Cells by HPLC-Coupled Tandem Mass Spectrometry.A SAMHD1 mutation associated with Aicardi-Goutières syndrome uncouples the ability of SAMHD1 to restrict HIV-1 from its ability to downmodulate type I interferon in humans.Synthesis of an arrayed sgRNA library targeting the human genome.A human inborn error connects the α's.
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Cytosolic RNA:DNA hybrids activate the cGAS-STING axis.
@en
type
label
Cytosolic RNA:DNA hybrids activate the cGAS-STING axis.
@en
prefLabel
Cytosolic RNA:DNA hybrids activate the cGAS-STING axis.
@en
P2093
P2860
P50
P356
P1433
P1476
Cytosolic RNA:DNA hybrids activate the cGAS-STING axis.
@en
P2093
Andrew V Kubarenko
Arun K Mankan
Dhruv Chauhan
Klara Höning
Liudmila Andreeva
Marion Goldeck
Moritz Gaidt
P2860
P304
P356
10.15252/EMBJ.201488726
P407
P577
2014-11-25T00:00:00Z