A T-to-G transversion at nucleotide -567 upstream of HBG2 in a GATA-1 binding motif is associated with elevated hemoglobin F.
about
Fetal globin gene repressors as drug targets for molecular therapies to treat the β-globinopathiesMi2β is required for γ-globin gene silencing: temporal assembly of a GATA-1-FOG-1-Mi2 repressor complex in β-YAC transgenic miceAn international effort to cure a global health problem: A report on the 19th Hemoglobin Switching Conference.Role of the GATA-1/FOG-1/NuRD pathway in the expression of human beta-like globin genes.Eos negatively regulates human γ-globin gene transcription during erythroid differentiation.Recombinant erythroid Kruppel-like factor fused to GATA1 up-regulates delta- and gamma-globin expression in erythroid cellsA 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expressionScreening of Transcription Factors Involved in Fetal Hemoglobin Regulation Using Phylogenetic Footprinting.Original Research: Generation of non-deletional hereditary persistence of fetal hemoglobin β-globin locus yeast artificial chromosome transgenic mouse models: -175 Black HPFH and -195 Brazilian HPFHThe Hellenic type of nondeletional hereditary persistence of fetal hemoglobin results from a novel mutation (g.-109G>T) in the HBG2 gene promoter.Role of STAT3 and GATA-1 interactions in gamma-globin gene expression.Diagnosis and prevention of thalassemia.Functional Analysis of an (A)γ-Globin Gene Promoter Variant (HBG1: g.-225_-222delAGCA) Underlines Its Role in Increasing Fetal Hemoglobin Levels Under Erythropoietic Stress.NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development.Pharmacological and molecular approaches for the treatment of β-hemoglobin disorders.Synergistic effect of two β globin gene cluster mutations leading to the hereditary persistence of fetal hemoglobin (HPFH) phenotype.Influences of genetic variation on fetal hemoglobin.Fetal hemoglobin induction in sickle erythroid progenitors using a synthetic zinc finger DNA-binding domain
P2860
Q26822810-0875DF69-CCD0-4F55-9515-631EB59F3BB8Q28484457-89490517-479D-44DD-ABA7-F1C9C8E308D1Q33850615-B8B4FF36-8471-463D-872B-18DECF55EDC1Q33963880-DF79D041-4870-42FE-96D8-0E1C5E4AA33FQ33988076-9213C04B-249D-4B27-8749-3C379740FB86Q34707219-0C111562-7525-4B7C-99EB-23BCD8F2D3B1Q35001653-0228AA09-144F-4FC0-AE31-2DEEAC25B475Q36218480-EA24637B-FC34-41F7-A007-B2746105605AQ36913598-920377FE-473A-411C-AB66-EE810132FE05Q37213400-F7C52759-E385-4E9E-BFE8-1C9D7F90E9FCQ37353689-575E3BC7-E792-41A7-B349-E59E3101AD01Q38167823-0DCE91CB-B988-4B83-BD54-59F8E3F5A280Q38819053-3F9750BF-2878-4889-8E94-6A67F1264EEFQ42912284-001E5E5E-F7A1-4991-A8AA-868ECDE34D00Q45874809-AA842FE3-6256-4FF1-8F2B-FB3F0E748325Q47844331-3C0B8C1E-5F3D-48BD-8C25-93DEDB718AD3Q54342522-8C2F4753-B84A-4872-ADD8-2AE963F592D6Q58776995-021BFE8F-8AE8-4384-B4EC-58F0691A1722
P2860
A T-to-G transversion at nucleotide -567 upstream of HBG2 in a GATA-1 binding motif is associated with elevated hemoglobin F.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A T-to-G transversion at nucle ...... ed with elevated hemoglobin F.
@en
type
label
A T-to-G transversion at nucle ...... ed with elevated hemoglobin F.
@en
prefLabel
A T-to-G transversion at nucle ...... ed with elevated hemoglobin F.
@en
P2093
P2860
P50
P356
P1476
A T-to-G transversion at nucle ...... ted with elevated hemoglobin F
@en
P2093
Cathy G Rosenfield
Daniel W H Mang
George P Patrinos
Lalana Nuntakarn
Raveen K Basran
Zhiyi Chen
P2860
P304
P356
10.1128/MCB.00071-08
P407
P577
2008-04-28T00:00:00Z