A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling.
about
Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1Getting 'Smad' about obesity and diabetesPredictive computational modeling to define effective treatment strategies for bone metastatic prostate cancer.miR-200c Regulation of Metastases in Ovarian Cancer: Potential Role in Epithelial and Mesenchymal Transition'Special k' and a loss of cell-to-cell adhesion in proximal tubule-derived epithelial cells: modulation of the adherens junction complex by ketamineNitric oxide and carbon monoxide antagonize TGF-β through ligand-independent internalization of TβR1/ALK5Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).Redundant roles of SMAD2 and SMAD3 in ovarian granulosa cells in vivo.Decreased levels of active SMAD2 correlate with poor prognosis in gastric cancer.Novel sequential ChIP and simplified basic ChIP protocols for promoter co-occupancy and target gene identification in human embryonic stem cells.Gene expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells.p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity.Sensing relative signal in the Tgf-β/Smad pathwayFibrotic protein expression profiles in penile tissue of patients with erectile dysfunctionBetaglycan alters NFκB-TGFβ2 cross talk to reduce survival of human granulosa tumor cells.Smad signaling in skeletal development and regeneration.TGF-beta biology in mammary development and breast cancer.The Functions of MicroRNA-200 Family in Ovarian Cancer: Beyond Epithelial-Mesenchymal Transition.The Signaling Mechanism of TGF-β1 Induced Bovine Mammary Epithelial Cell Apoptosis.An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancerRequirement of a dynein light chain in TGFbeta/Smad3 signaling.High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cellsGenetic evidence that SMAD2 is not required for gonadal tumor development in inhibin-deficient miceMutations in protein-binding hot-spots on the hub protein Smad3 differentially affect its protein interactions and Smad3-regulated gene expressionTumor suppressor microRNA-27a in colorectal carcinogenesis and progression by targeting SGPP1 and Smad2SMAD2 is essential for TGF beta-mediated Th17 cell generation.Characterisation of the vitreous proteome in proliferative diabetic retinopathy.Autocrine transforming growth factor-{beta}1 activation mediated by integrin {alpha}V{beta}3 regulates transcriptional expression of laminin-332 in Madin-Darby canine kidney epithelial cellsUpregulation of transforming growth factor-β signaling in a rat model of rotator cuff tears.HDAC6 deacetylase activity is required for hypoxia-induced invadopodia formation and cell invasion.Curcumin inhibits cobalt chloride-induced epithelial-to-mesenchymal transition associated with interference with TGF-β/Smad signaling in hepatocytes.Pancreatic cancer cells respond to type I collagen by inducing snail expression to promote membrane type 1 matrix metalloproteinase-dependent collagen invasion.A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary glandSmad2 protein disruption in the central nervous system leads to aberrant cerebellar development and early postnatal ataxia in miceCoordinated and interactive expression of genes of lipid metabolism and inflammation in adipose tissue and liver during metabolic overload.SMAD3 rs17228212 gene polymorphism is associated with reduced risk to cerebrovascular accidents and subclinical atherosclerosis in anti-CCP negative Spanish rheumatoid arthritis patients.Adamts5 deletion blocks murine dermal repair through CD44-mediated aggrecan accumulation and modulation of transforming growth factor β1 (TGFβ1) signaling.Smad2 and PEA3 cooperatively regulate transcription of response gene to complement 32 in TGF-β-induced smooth muscle cell differentiation of neural crest cells.The Local Control of the Pituitary by Activin Signaling and Modulation.Mutant p53 promotes tumor cell malignancy by both positive and negative regulation of the transforming growth factor β (TGF-β) pathway.
P2860
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P2860
A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A tale of two proteins: differ ...... d Smad3 in TGF-beta signaling.
@en
type
label
A tale of two proteins: differ ...... d Smad3 in TGF-beta signaling.
@en
prefLabel
A tale of two proteins: differ ...... d Smad3 in TGF-beta signaling.
@en
P2860
P356
P1476
A tale of two proteins: differ ...... d Smad3 in TGF-beta signaling.
@en
P2093
Kimberly A Brown
P2860
P356
10.1002/JCB.21255
P577
2007-05-01T00:00:00Z