Structure and expression of germ line immunoglobulin heavy-chain epsilon transcripts: interleukin-4 plus lipopolysaccharide-directed switching to C epsilon.
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Sequences of human immunoglobulin switch regions: implications for recombination and transcriptionmRNA transcripts initiating within the human immunoglobulin mu heavy chain enhancer region contain a non-translatable exon and are extremely heterogeneous at the 5' endRelated Mechanisms of Antibody Somatic Hypermutation and Class Switch RecombinationInterleukin 5 (IL-5) provides a signal that is required in addition to IL-4 for isotype switching to immunoglobulin (Ig) G1 and IgE.Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity.Use of chromatin immunoprecipitation (ChIP) to detect transcription factor binding to highly homologous promoters in chromatin isolated from unstimulated and activated primary human B cells.T-cell receptor V elements regulate murine IgE production and airways responsiveness.Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination.Effect of CpG dinucleotides within IgH switch region repeats on immunoglobulin class switch recombination.Divide and conquer: the importance of cell division in regulating B-cell responses.An antisense oligonucleotide complementary to a sequence in I gamma 2b increases gamma 2b germline transcripts, stimulates B cell DNA synthesis, and inhibits immunoglobulin secretion.Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching.Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50.Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers.Recombinant CD40 ligand stimulation of murine B cell growth and differentiation: cooperative effects of cytokines.Nonhomologous recombination at sites within the mouse JH-C delta locus accompanies C mu deletion and switch to immunoglobulin D secretion.Transcriptional regulatory elements stimulate recombination in extrachromosomal substrates carrying immunoglobulin switch-region sequencesS region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process.The transcriptional regulator NFIL3 controls IgE production.TRIF signaling is essential for TLR4-driven IgE class switching.Interleukin 4-inducible phosphorylation of HMG-I(Y) is inhibited by rapamycin.Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germ line epsilon transcripts.A transcriptional serenAID: the role of noncoding RNAs in class switch recombination.Evidence that immunoglobulin VH-DJ recombination does not require germ line transcription of the recombining variable gene segment.RNA:DNA complex formation upon transcription of immunoglobulin switch regions: implications for the mechanism and regulation of class switch recombination.STF-IL-4: a novel IL-4-induced signal transducing factor.CREB/ATF proteins enhance the basal and CD154- and IL-4-induced transcriptional activity of the human Igamma1 proximal promoter.A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon.Regulation of IgE production and other immunopathogenetic mechanisms.The non-histone chromosomal protein HMG-I(Y) contributes to repression of the immunoglobulin heavy chain germ-line epsilon RNA promoter.Enhancement of IgE synthesis in the human myeloma cell line U-266 with an IgE binding factor from a human T-cell line.Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production.High-level expression of a human immunoglobulin gamma 1 transgene depends on switch region sequences.Structure and expression of mouse germline immunoglobulin gamma 3 heavy chain transcripts induced by the mitogen lipopolysaccharide.Immunoglobulin genes undergo legitimate repair in human B cells not only after cis- but also frequent trans-class switch recombination.Translatable immunoglobulin germ-line transcript.Structural analysis of human gamma 3 intervening regions and switch regions: implication for the low frequency of switching in IgG3-deficient patients.Expression of IgE heavy chain transcripts in the sinus mucosa of atopic and nonatopic patients with chronic sinusitis.Interallelic class switch recombination can reverse allelic exclusion and allowtrans-complementation of an IgH locus switching defectThe Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination
P2860
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P2860
Structure and expression of germ line immunoglobulin heavy-chain epsilon transcripts: interleukin-4 plus lipopolysaccharide-directed switching to C epsilon.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Structure and expression of ge ...... rected switching to C epsilon.
@ast
Structure and expression of ge ...... rected switching to C epsilon.
@en
type
label
Structure and expression of ge ...... rected switching to C epsilon.
@ast
Structure and expression of ge ...... rected switching to C epsilon.
@en
prefLabel
Structure and expression of ge ...... rected switching to C epsilon.
@ast
Structure and expression of ge ...... rected switching to C epsilon.
@en
P2093
P2860
P356
P1476
Structure and expression of ge ...... rected switching to C epsilon.
@en
P2093
P2860
P304
P356
10.1128/MCB.10.4.1672
P407
P577
1990-04-01T00:00:00Z