Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching.
about
Molecular regulation of class switch recombination to IgE through epsilon germline transcription.Strand specificity in the transcriptional targeting of recombination at immunoglobulin switch sequences.Human antibodies from transgenic mice.Negative regulation of activation-induced cytidine deaminase in B cellsHeavy-chain isotype patterns of human antibody-secreting cells induced by Haemophilus influenzae type b conjugate vaccines in relation to age and preimmunity.Downstream boundary of chromosomal R-loops at murine switch regions: implications for the mechanism of class switch recombination.Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus.AID to overcome the limitations of genomic information by introducing somatic DNA alterations.R-loop-mediated genomic instability is caused by impairment of replication fork progressionNucleolin is one component of the B cell-specific transcription factor and switch region binding protein, LR1.Quantitative regulation of class switch recombination by switch region transcription.H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutationVisualization of the genesis and fate of isotype-switched B cells during a primary immune responseATM is required for efficient recombination between immunoglobulin switch regions.Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers.G clustering is important for the initiation of transcription-induced R-loops in vitro, whereas high G density without clustering is sufficient thereafterVasoactive intestinal peptide induces S(alpha)/S(mu) switch circular DNA in human B cells.S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process.The transcriptional regulator NFIL3 controls IgE production.Interleukin 4-inducible phosphorylation of HMG-I(Y) is inhibited by rapamycin.A transcriptional serenAID: the role of noncoding RNAs in class switch recombination.Class-Switch Recombination in the Absence of the IgH 3' Regulatory Region.Evidence that immunoglobulin VH-DJ recombination does not require germ line transcription of the recombining variable gene segment.RNA:DNA complex formation upon transcription of immunoglobulin switch regions: implications for the mechanism and regulation of class switch recombination.Mechanism of R-loop formation at immunoglobulin class switch sequences.AML and Ets proteins regulate the I alpha1 germ-line promoter.Competition between the RNA transcript and the nontemplate DNA strand during R-loop formation in vitro: a nick can serve as a strong R-loop initiation site.
P2860
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P2860
Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Replacement of germ-line epsil ...... n heavy chain class switching.
@ast
Replacement of germ-line epsil ...... n heavy chain class switching.
@en
type
label
Replacement of germ-line epsil ...... n heavy chain class switching.
@ast
Replacement of germ-line epsil ...... n heavy chain class switching.
@en
prefLabel
Replacement of germ-line epsil ...... n heavy chain class switching.
@ast
Replacement of germ-line epsil ...... n heavy chain class switching.
@en
P2093
P2860
P356
P1476
Replacement of germ-line epsil ...... n heavy chain class switching.
@en
P2093
P2860
P304
P356
10.1073/PNAS.90.8.3705
P407
P577
1993-04-01T00:00:00Z