The bcl-2 candidate proto-oncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation
about
PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1Noxa/Bcl-2 protein interactions contribute to bortezomib resistance in human lymphoid cellsEvidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxesOverexpressed full-length human BCL2 extends the survival of baculovirus-infected Sf9 insect cellsbcl-2 gene enables rescue from in vitro myelosuppression (bone marrow cell death) induced by chemotherapyThe p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/MMCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activityMovement of Bax from the cytosol to mitochondria during apoptosisThe structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activityAltered methional homoeostasis is associated with decreased apoptosis in BAF3 bcl2 murine lymphoid cellsA splicing variant of the Bcl-2 member Bok with a truncated BH3 domain induces apoptosis but does not dimerize with antiapoptotic Bcl-2 proteins in vitroBcl-2 protein expression during murine developmentDr. Josef Steiner Cancer Research Prize Lecture: the role of physiological cell death in neoplastic transformation and in anti-cancer therapy.Oligomerization of membrane-bound Bcl-2 is involved in its pore formation induced by tBid.Tissue-specific Bcl-2 protein partners in apoptosis: An ovarian paradigm.Immunohistochemical profile of endometrial adenocarcinoma: a study of 61 cases and review of the literature.Meiotic recombination between yeast artificial chromosomes yields a single clone containing the entire BCL2 protooncogeneBcl-2 and Bax interact via the BH1-3 groove-BH3 motif interface and a novel interface involving the BH4 motifActivation of cyclin A-dependent protein kinases during apoptosisApoptosis in the development of the immune system: growth factors, clonal selection and bcl-2.Absence of t(14;18) major and minor breakpoints and of Bcl-2 protein overproduction in Reed-Sternberg cells of Hodgkin's disease.Follicular lymphomas of the gastrointestinal tract. Pathologic features in 31 cases and bcl-2 oncogenic protein expressionExpression of bcl-2 in fetal tissues suggests a role in morphogenesis.Detection of the apoptosis-suppressing oncoprotein bc1-2 in hormone-refractory human prostate cancers.Bcl-2 expression in normal endometrium during the menstrual cycle.bcl-2 in normal human breast and carcinoma, association with oestrogen receptor-positive, epidermal growth factor receptor-negative tumours and in situ cancer.BCL2 oncogene translocation is mediated by a chi-like consensus.The protein bcl-2 alpha does not require membrane attachment, but two conserved domains to suppress apoptosisVariable functions of bcl-2 in mediating bioreactor stress- induced apoptosis in hybridoma cellsClinicopathological significance of PTEN and bcl2 expressions in oral squamous cell carcinomaCellular response to endoplasmic reticulum stress: a matter of life or death.The T cell receptor repertoire of CD4-8+ thymocytes is altered by overexpression of the BCL-2 protooncogene in the thymus.Cell death regulation by B-cell lymphoma protein.Bcl-2-family proteins and hematologic malignancies: history and future prospects.Apoptosis induced by t10,c12-conjugated linoleic acid is mediated by an atypical endoplasmic reticulum stress responseMyc-mediated apoptosis is blocked by ectopic expression of Bcl-2Complementation by BCL2 and C-HA-RAS oncogenes in malignant transformation of rat embryo fibroblastsSurface expression of Bcl-2 in chronic lymphocytic leukemia and other B-cell leukemias and lymphomas without a breakpoint t(14;18).Bcl-2 family on guard at the ER.
P2860
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P2860
The bcl-2 candidate proto-oncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
The bcl-2 candidate proto-onco ...... ing the t(14;18) translocation
@ast
The bcl-2 candidate proto-onco ...... ing the t(14;18) translocation
@en
type
label
The bcl-2 candidate proto-onco ...... ing the t(14;18) translocation
@ast
The bcl-2 candidate proto-onco ...... ing the t(14;18) translocation
@en
prefLabel
The bcl-2 candidate proto-onco ...... ing the t(14;18) translocation
@ast
The bcl-2 candidate proto-onco ...... ing the t(14;18) translocation
@en
P2093
P2860
P356
P1476
The bcl-2 candidate proto-onco ...... ing the t(14;18) translocation
@en
P2093
P2860
P304
P356
10.1128/MCB.9.2.701
P407
P577
1989-02-01T00:00:00Z