Modulation of the immunological synapse: a key to HIV-1 pathogenesis?
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Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapseDendritic Cells in HIV-1 and HCV Infection: Can They Help Win the Battle?How HIV takes advantage of the cytoskeleton in entry and replicationLipids and membrane microdomains in HIV-1 replicationWhere in the Cell Are You? Probing HIV-1 Host Interactions through Advanced Imaging TechniquesMolecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor NefNef does not contribute to replication differences between R5 pre-AIDS and AIDS HIV-1 clones from patient ACH142Manipulating CD4+ T cells by optical tweezers for the initiation of cell-cell transfer of HIV-1.Tetherin restricts direct cell-to-cell infection of HIV-1.HIV-1 Nef employs two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling.Protein protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef proteinHIV-1 infection of DC: evidence for the acquisition of virus particles from infected T cells by antigen uptake mechanism.Nef, macrophages and B cells: a highway for evasionThe roles of tetraspanins in HIV-1 replication.LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytesThe Role of Lipids in Retrovirus Replication.HIV-1 Nef enhances dendritic cell-mediated viral transmission to CD4+ T cells and promotes T-cell activation.HIV-1 Nef: a multifaceted modulator of T cell receptor signaling.The SCHOOL of nature: III. From mechanistic understanding to novel therapiesCytonemes and tunneling nanotubules in cell-cell communication and viral pathogenesis.Lentiviral Nef proteins manipulate T cells in a subset-specific mannerRelease of HIV-1 sequestered in the vesicles of oral and genital mucosal epithelial cells by epithelial-lymphocyte interaction.Viral modulation of T-cell receptor signalingChronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug.Nef modulates the immunogenicity of Gag encoded in a non-infectious HIV DNA vaccineBiology of HIV mucosal transmission.Determinants in HIV-1 Nef for enhancement of virus replication and depletion of CD4+ T lymphocytes in human lymphoid tissue ex vivoIntercellular adhesion molecule 1 (ICAM-1), but not ICAM-2 and -3, is important for dendritic cell-mediated human immunodeficiency virus type 1 transmission.Mechanisms of HIV-1 Nef function and intracellular signaling.HIV-1 at the immunological and T-lymphocytic virological synapse.HIV-1 Trans Infection of CD4(+) T Cells by Professional Antigen Presenting CellsThe remarkable frequency of human immunodeficiency virus type 1 genetic recombinationThe inability to disrupt the immunological synapse between infected human T cells and APCs distinguishes HIV-1 from most other primate lentiviruses.HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits.The tumour suppressor APC promotes HIV-1 assembly via interaction with Gag precursor protein.Functional anatomy of T cell activation and synapse formation.Dendritic cell-lymphocyte cross talk downregulates host restriction factor SAMHD1 and stimulates HIV-1 replication in dendritic cellsVirus cell-to-cell transmission.Orchestrating cytoskeleton and intracellular vesicle traffic to build functional immunological synapses.Adding new dimensions: towards an integrative understanding of HIV-1 spread.
P2860
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P2860
Modulation of the immunological synapse: a key to HIV-1 pathogenesis?
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Modulation of the immunological synapse: a key to HIV-1 pathogenesis?
@ast
Modulation of the immunological synapse: a key to HIV-1 pathogenesis?
@en
type
label
Modulation of the immunological synapse: a key to HIV-1 pathogenesis?
@ast
Modulation of the immunological synapse: a key to HIV-1 pathogenesis?
@en
prefLabel
Modulation of the immunological synapse: a key to HIV-1 pathogenesis?
@ast
Modulation of the immunological synapse: a key to HIV-1 pathogenesis?
@en
P2860
P356
P1476
Modulation of the immunological synapse: a key to HIV-1 pathogenesis?
@en
P2093
Andres Alcover
P2860
P304
P356
10.1038/NRI2041
P577
2007-04-01T00:00:00Z