Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement.
about
Dendritic Cells in HIV-1 and HCV Infection: Can They Help Win the Battle?Crystal Structure of NFAT Bound to the HIV-1 LTR Tandem κB Enhancer ElementStructural Basis of HIV-1 Activation by NF-κB—A Higher-Order Complex of p50:RelA Bound to the HIV-1 LTRPseudo-merohedral twinning and noncrystallographic symmetry in orthorhombic crystals of SIVmac239 Nef core domain bound to different-length TCRζ fragmentsOne protein to rule them all: modulation of cell surface receptors and molecules by HIV Nef.A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12HIV-1 Nef-mediated T-cell activation and chemotaxis are decoupled using a HIV-1/SIVpbj1.9. chimeric nef variant.Human T-cell leukemia virus type 1 p8 protein increases cellular conduits and virus transmission.Going wild: lessons from naturally occurring T-lymphotropic lentivirusesInefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infectionThe HIV envelope but not VSV glycoprotein is capable of mediating HIV latent infection of resting CD4 T cellsPatterns of HIV-1 protein interaction identify perturbed host-cellular subsystemsHIV-1 gp41 and TCRalpha trans-membrane domains share a motif exploited by the HIV virus to modulate T-cell proliferationCounteraction of HLA-C-mediated immune control of HIV-1 by Nef.HIV-1 Nef: a multifaceted modulator of T cell receptor signaling.Structural constraints on human immunodeficiency virus type 1 Nef function.The SCHOOL of nature: III. From mechanistic understanding to novel therapiesCalcium/calcineurin synergizes with prostratin to promote NF-κB dependent activation of latent HIVLentiviral Nef proteins manipulate T cells in a subset-specific mannerThe cytoplasmic domain of the HIV-1 glycoprotein gp41 induces NF-κB activation through TGF-β-activated kinase 1.Inhibition of T-cell receptor signal transduction and viral expression by the linker for activation of T cells-interacting p12(I) protein of human T-cell leukemia/lymphoma virus type 1.Commitment to apoptosis in CD4(+) T lymphocytes productively infected with human immunodeficiency virus type 1 is initiated by lysosomal membrane permeabilization, itself induced by the isolated expression of the viral protein NefViral modulation of T-cell receptor signalingModulation of the immunological synapse: a key to HIV-1 pathogenesis?Activation/proliferation and apoptosis of bystander goat lymphocytes induced by a macrophage-tropic chimeric caprine arthritis encephalitis virus expressing SIV Nef.Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line.Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664.HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cellsThe frantic play of the concealed HIV envelope cytoplasmic tail.Deployment of the human immunodeficiency virus type 1 protein arsenal: combating the host to enhance viral transcription and providing targets for therapeutic developmentConservation of Nef function across highly diverse lineages of SIVsmm.Measurement of human immunodeficiency virus type 1 preintegration transcription by using Rev-dependent Rev-CEM cells reveals a sizable transcribing DNA population comparable to that from proviral templates.The inability to disrupt the immunological synapse between infected human T cells and APCs distinguishes HIV-1 from most other primate lentiviruses.Adult AIDS-like disease in a novel inducible human immunodeficiency virus type 1 Nef transgenic mouse model: CD4+ T-cell activation is Nef dependent and can occur in the absence of lymphophenia.Viremic long-term nonprogressive HIV-1 infection is not associated with abnormalities in known Nef functionsOrchestrating cytoskeleton and intracellular vesicle traffic to build functional immunological synapses.Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2.Identification and characterization of a long non-coding RNA up-regulated during HIV-1 infection.Primate Lentiviruses Modulate NF-κB Activity by Multiple Mechanisms to Fine-Tune Viral and Cellular Gene Expression.HIV-1 Nef and T-cell activation: a history of contradictions.
P2860
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P2860
Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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name
Nef is physically recruited in ...... on early after TCR engagement.
@en
Nef is physically recruited in ...... on early after TCR engagement.
@nl
type
label
Nef is physically recruited in ...... on early after TCR engagement.
@en
Nef is physically recruited in ...... on early after TCR engagement.
@nl
prefLabel
Nef is physically recruited in ...... on early after TCR engagement.
@en
Nef is physically recruited in ...... on early after TCR engagement.
@nl
P2093
P1476
Nef is physically recruited in ...... on early after TCR engagement.
@en
P2093
Carlos de Noronha
Marielle Cavrois
Samuel A Williams
Warner C Greene
Wes Yonemoto
P304
P356
10.4049/JIMMUNOL.175.9.6050
P407
P50
P577
2005-11-01T00:00:00Z