Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen.
about
Ku is associated with the telomere in mammalsProteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cellsDNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigenRegulation of Rad51 function by c-Abl in response to DNA damageRepression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complexDNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding propertiesGene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sitesA DNA-activated protein kinase from HeLa cell nucleip95vav associates with the nuclear protein Ku-70Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase.Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks.The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosisBinding of Ku and c-Abl at the kinase homology region of DNA-dependent protein kinase catalytic subunitRare microsatellite polymorphisms in the DNA repair genes XRCC1, XRCC3 and XRCC5 associated with cancer in patients of varying radiosensitivityInteraction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acidsIn vitro analysis of the zinc-finger motif in human replication protein ARegulation of DNA-dependent protein kinase by the Lyn tyrosine kinase.Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.Involvement of DNA-dependent protein kinase in UV-induced replication arrest.Roles of replication protein A and DNA-dependent protein kinase in the regulation of DNA replication following DNA damage.Two-Stage Synapsis of DNA Ends during Non-homologous End Joining.Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase.The plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner.Orphan receptor TR3 enhances p53 transactivation and represses DNA double-strand break repair in hepatoma cells under ionizing radiation.Equine severe combined immunodeficiency: a defect in V(D)J recombination and DNA-dependent protein kinase activity.Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosisGene for the catalytic subunit of mouse DNA-dependent protein kinase maps to the scid locus.Mechanisms of switching on p53: a role for covalent modification?The BCL2 major breakpoint region is a sequence- and cell-cycle-specific binding site of the Ku antigenEBNA-LP associates with cellular proteins including DNA-PK and HA95.Non-homologous end joining: emerging themes and unanswered questions.Activation and autoregulation of DNA-PK from structured single-stranded DNA and coding end hairpins.The DNA-damage response: new molecular insights and new approaches to cancer therapyDNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53.Two cellular protein kinases, DNA-PK and PKA, phosphorylate the adenoviral L4-33K protein and have opposite effects on L1 alternative RNA splicingThe DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication.Suppression of heat-induced hsp70 expression by the 70-kDa subunit of the human Ku autoantigenDNA-PK-dependent binding of DNA ends to plasmids containing nuclear matrix attachment region DNA sequences: evidence for assembly of a repair complex.
P2860
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P2860
Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Human cells contain a DNA-acti ...... and the human Ku autoantigen.
@ast
Human cells contain a DNA-acti ...... and the human Ku autoantigen.
@en
type
label
Human cells contain a DNA-acti ...... and the human Ku autoantigen.
@ast
Human cells contain a DNA-acti ...... and the human Ku autoantigen.
@en
prefLabel
Human cells contain a DNA-acti ...... and the human Ku autoantigen.
@ast
Human cells contain a DNA-acti ...... and the human Ku autoantigen.
@en
P2093
P2860
P356
P1476
Human cells contain a DNA-acti ...... and the human Ku autoantigen.
@en
P2093
C W Anderson
S P Lees-Miller
P2860
P304
P356
10.1128/MCB.10.12.6472
P407
P577
1990-12-01T00:00:00Z