Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells.
about
Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathwayA direct binding site for Grb2 contributes to transformation and leukemogenesis by the Tel-Abl (ETV6-Abl) tyrosine kinaseThe (6;9) chromosome translocation, associated with a specific subtype of acute nonlymphocytic leukemia, leads to aberrant transcription of a target gene on 9q34Tyrosine phosphorylation of BCR by FPS/FES protein-tyrosine kinases induces association of BCR with GRB-2/SOSAssociation of HLA Class I and Class II genes with bcr-abl transcripts in leukemia patients with t(9;22) (q34;q11)Current concepts in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemiaMolecular requirements for rapid plasmacytoma and pre-B lymphoma induction by Abelson murine leukemia virus in myc-transgenic mice.Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitorBCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias.Molecular mechanisms of cancer.BCR/ABL transcripts and leukemia phenotype: an unsolved puzzle.Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.Temperature-sensitive transformation by an Abelson virus mutant encoding an altered SH2 domain.Signaling by ABL oncogenes through cyclin D1.Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2.Preparation and application of antibodies to phosphoamino acid sequences.Expression of p210 and p190 BCR-ABL due to alternative splicing in chronic myelogenous leukaemia.Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies.SH2-containing inositol 5'-phosphatase inhibits transformation of Abelson murine leukemia virus.A requirement for NF-kappaB activation in Bcr-Abl-mediated transformationOncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathwayPhosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutantsBCR/ABL inhibition by an escort/phosphatase fusion proteinPhiladelphia positive acute lymphoblastic leukaemia of childhood.Sustained suppression of Bcr-Abl-driven lymphoid leukemia by microRNA mimics.The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity.BCR-ABL and v-abl oncogenes induce distinct patterns of thymic lymphoma involving different lymphocyte subsets.Hyperexpression of interleukin-7 is not necessary or sufficient for transformation of a pre-B lymphoid cell line.Characterization of the BCR promoter in Philadelphia chromosome-positive and -negative cell lines.Btk dosage determines sensitivity to B cell antigen receptor cross-linkingDifferences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogeneDistinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1.Chronic myeloid leukemia (CML) with P190 BCR-ABL: analysis of characteristics, outcomes, and prognostic significanceT-cell immunity to the joining region of p210BCR-ABL proteinMolecular analysis of the Philadelphia chromosome.Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteinsA 41-kilodalton protein is a potential substrate for the p210bcr-abl protein-tyrosine kinase in chronic myelogenous leukemia cells.Molecular diagnosis and monitoring in the clinical management of patients with chronic myelogenous leukemia treated with tyrosine kinase inhibitors.Blast crisis in a murine model of chronic myelogenous leukemia.Can anthocyanins improve maintenance therapy of Ph(+) acute lymphoblastic leukaemia?
P2860
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P2860
Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Alternative forms of the BCR-A ...... on of immature lymphoid cells.
@ast
Alternative forms of the BCR-A ...... on of immature lymphoid cells.
@en
type
label
Alternative forms of the BCR-A ...... on of immature lymphoid cells.
@ast
Alternative forms of the BCR-A ...... on of immature lymphoid cells.
@en
prefLabel
Alternative forms of the BCR-A ...... on of immature lymphoid cells.
@ast
Alternative forms of the BCR-A ...... on of immature lymphoid cells.
@en
P2093
P2860
P356
P1476
Alternative forms of the BCR-A ...... on of immature lymphoid cells.
@en
P2093
Chianese E
McLaughlin J
P2860
P304
P356
10.1128/MCB.9.5.1866
P407
P577
1989-05-01T00:00:00Z