Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?
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Oncogenic Intra-p53 Family Member Interactions in Human CancersThe Contrived Mutant p53 Oncogene - Beyond Loss of FunctionsReactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancerLinks between mutant p53 and genomic instabilityTumor suppressor p53 and its gain-of-function mutants in cancerInvolvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ)Structural evolution of p53, p63, and p73: Implication for heterotetramer formationDNA damage response genes and the development of cancer metastasisArsenic trioxide reactivates proteasome-dependent degradation of mutant p53 protein in cancer cells in part via enhanced expression of Pirh2 E3 ligaseIdentification of colorectal cancer patients with tumors carrying the TP53 mutation on the codon 72 proline allele that benefited most from 5-fluorouracil (5-FU) based postoperative chemotherapy.Integrating Multi-omics Data to Dissect Mechanisms of DNA repair Dysregulation in Breast CancerSmall-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway.A new isoquinolinium derivative, Cadein1, preferentially induces apoptosis in p53-defective cancer cells with functional mismatch repair via a p38-dependent pathway.A planarian p53 homolog regulates proliferation and self-renewal in adult stem cell lineagesCharacterization of a new mouse p53 variant: loss-of-function and gain-of-function.Targeting p53 for Novel Anticancer Therapy.RNPC1, an RNA-binding protein and a target of the p53 family, regulates p63 expression through mRNA stability.Tracing the protectors path from the germ line to the genome.The role of mutant p53 in human cancer.p63 and p73 coordinate p53 function to determine the balance between survival, cell death, and senescence in adult neural precursor cells.Molecular mechanism of mutant p53 stabilization: the role of HSP70 and MDM2.Use of conventional and -omics based methods for health claims of dietary antioxidants: a critical overview.Mutant p53 protein is targeted by arsenic for degradation and plays a role in arsenic-mediated growth suppression.Propagation of aggregated p53: Cross-reaction and coaggregation vs. seeding.A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis.Induction of apoptotic genes by a p73-phosphatase and tensin homolog (p73-PTEN) protein complex in response to genotoxic stress.TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73.The p53R172H mutant does not enhance hepatocellular carcinoma development and progression.Mutant p53 cooperates with ETS2 to promote etoposide resistance.Mutant p53: one name, many proteins.Mutant p53-R273H mediates cancer cell survival and anoikis resistance through AKT-dependent suppression of BCL2-modifying factor (BMF).MicroRNAs, wild-type and mutant p53: more questions than answers.Evaluating Drosophila p53 as a model system for studying cancer mutationsp63 expression confers significantly better survival outcomes in high-risk diffuse large B-cell lymphoma and demonstrates p53-like and p53-independent tumor suppressor function.TAp73 knockout shows genomic instability with infertility and tumor suppressor functions.Induction of genetic instability by gain-of-function p53 cancer mutants.MicroRNA-20a-5p contributes to hepatic glycogen synthesis through targeting p63 to regulate p53 and PTEN expression.p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene.Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.Aberrant cytoplasmic expression of p63 and prostate cancer mortality.
P2860
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P2860
Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?
@ast
Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?
@en
type
label
Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?
@ast
Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?
@en
prefLabel
Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?
@ast
Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?
@en
P2860
P356
P1433
P1476
Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?
@en
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210311
P407
P577
2007-04-01T00:00:00Z